{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:44:47Z","timestamp":1775177087758,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>The present study aimed to evaluate the early and 1\u2010year outcomes of using percutaneous mechanical circulatory support (MCS) devices in patients undergoing high\u2010risk chronic total occlusion (CTO) percutaneous coronary intervention (PCI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective registry cohort study that enrolled patients undergoing high\u2010risk elective CTO\u2010PCI with MCS device support and patients without MCS device support. The primary endpoint was major adverse cardiac events (MACE) at 1\u2010year follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 2349 patients were enrolled, comprising 151 in the MCS group and 2198 in the non\u2010MCS group. Compared with the non\u2010MCS group, the MCS group exhibited a lower left ventricular ejection fraction (LVEF) (41.6\u2009\u00b1\u200910.4% vs. 50.4\u2009\u00b1\u20098.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and a higher prevalence of two\u2010vessel CTO (30.5% vs. 18.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and three\u2010vessel CTO (5.3% vs. 1.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After propensity score matching (PSM), 137 patients in each group with comparable propensity scores were included for analysis. The cohort had a mean age of 65.97\u2009\u00b1\u200910.00 years, with 83.94% male participants. The most common MCS devices were IABP alone (66.42%), followed by ECMO\u2009+\u2009IABP (26.28%) and ECMO alone (7.30%). The MCS group demonstrated significantly higher technical success rates than the non\u2010MCS group (95.62% vs. 87.59%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027) but comparable procedural success rates (86.13% vs. 83.94%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.611). Complete revascularization rates were significantly higher in the MCS group (89.05% vs. 66.42%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). No differences occurred in 1\u2010year MACE incidence or its components between groups, and MCS device use showed no correlation with 1\u2010year MACE risk.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MCS\u2010supported CTO\u2010PCI improves technical success rates and complete revascularization achievement rates during the index procedure. However, MCS is associated with a significantly higher incidence of in\u2010hospital MACE and device\u2010related complications, despite showing no significant difference in 1\u2010year MACE rates compared to conventional CTO\u2010PCI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70137","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T04:20:37Z","timestamp":1757910037000},"page":"3160-3170","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mid\u2010Term Efficacy and Safety of Mechanical Circulatory Support in High\u2010Risk Elective Chronic Total Occlusion Percutaneous Coronary Intervention: A Prospective Propensity\u2010Matched Cohort Study"],"prefix":"10.1002","volume":"106","author":[{"given":"Tiantong","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"},{"name":"Department of Cardiology Air Force Hospital of Western Theater Command Chengdu Sichuan People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bohui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"},{"name":"School of Public Health Shaanxi University of Chinese Medicine Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boda","family":"Zhu","sequence":"additional","affiliation":[{"name":"Primary Flight Training Base Air Force Aviation University Harbin People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youhu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology No.971 Hospital of the PLA Navy Qingdao Shandong People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"},{"name":"School of Clinical Medicine Xi'an Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"},{"name":"PLA 981 Hospital Joint Logistics Support Force Chengde Hebei People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genrui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Lian","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an Shaanxi People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengxiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xijing Hospital The Fourth Military Medical University Xi'an 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