{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:34:03Z","timestamp":1787164443440,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter aortic valve implantation (TAVI) for the treatment of bicuspid aortic valve (BAV) is still debated. Although several registries reported favorable outcomes with various transcatheter heart valves (THV) in BAV, there is no published data on the Navitor platform.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To provide preliminary data on the efficacy and the safety of the Navitor valve in BAV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively included patients who underwent TAVI using the Navitor valve (Abbott, Minneapolis, Minnesota, USA) for severe aortic stenosis in BAV anatomies, from October 2021 until August 2024. Patients were enrolled at six high TAVI volume centers. The endpoints were procedural device success and early safety, according to the VARC\u20103 criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 47 patients were included in this registry. The mean age was 83.7\u2009\u00b1\u20097.9, and 66% of the patients were women. Bicuspid type 1 L\u2010R fusion (72.3%) was the dominant anatomical subtype. A high device success rate was achieved: 91.5% in\u2010hospital and 91.1% at 30\u2010day follow\u2010up, while early safety was 70.2% in\u2010hospital and 66.7% at 30 days. No 30\u2010day prosthesis\u2010patient mismatch (PPM) and no \u2265moderate paravalvular regurgitation (PVR) were observed at 30 days; meanwhile, rates of permanent pacemaker implantation (PPI) were not negligible (23.4% in\u2010hospital and 26.7% at 30\u2010day follow\u2010up).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Navitor THV appears to be a safe and effective treatment option for patients with severe bicuspid aortic stenosis. Larger registries and comparison with different platforms are required to validate these outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70186","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T04:16:32Z","timestamp":1758168992000},"page":"3265-3270","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The NavIIgister: Transcatheter Aortic Valve Implantation With the Navitor Platform in Bicuspid Anatomy"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5538-5222","authenticated-orcid":false,"given":"Omar A.","family":"Oliva","sequence":"first","affiliation":[{"name":"Groupe Cardio\u2010Vasculaire Interventionnel Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Criscione","sequence":"additional","affiliation":[{"name":"Department of Clinical and Interventional Cardiology IRCCS Policlinico San Donato San Donato Milanese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1998-6370","authenticated-orcid":false,"given":"Matteo","family":"Casenghi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Sant'Andrea Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8937-437X","authenticated-orcid":false,"given":"Davorka","family":"Lulic","sequence":"additional","affiliation":[{"name":"Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Zuffi","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute of Caen Saint Martin Private Hospital Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3554-6938","authenticated-orcid":false,"given":"Federico","family":"De Marco","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino IRCCS Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Barbato","sequence":"additional","affiliation":[{"name":"Division of Cardiology Sant'Andrea Hospital Rome Italy"},{"name":"Department of Clinical and Molecular Medicine Sapienza University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4687-3686","authenticated-orcid":false,"given":"Luca","family":"Testa","sequence":"additional","affiliation":[{"name":"Department of Clinical and Interventional Cardiology IRCCS Policlinico San Donato San Donato Milanese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bedogni","sequence":"additional","affiliation":[{"name":"Department of Clinical and Interventional Cardiology IRCCS Policlinico San Donato San Donato Milanese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9674-0278","authenticated-orcid":false,"given":"Ole","family":"De Backer","sequence":"additional","affiliation":[{"name":"Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Dumonteil","sequence":"additional","affiliation":[{"name":"Groupe Cardio\u2010Vasculaire Interventionnel Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Tch\u00e9tch\u00e9","sequence":"additional","affiliation":[{"name":"Groupe Cardio\u2010Vasculaire Interventionnel Clinique Pasteur Toulouse 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