{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:50:48Z","timestamp":1773103848923,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T00:00:00Z","timestamp":1762646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Atrial septal defect (ASD) is a common congenital heart anomaly causing a significant hemodynamic burden if untreated. Transcatheter closure is a minimally invasive standard treatment, but prospective data on short\u2010term cardiac remodeling are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate short\u2010term echocardiographic changes in cardiac structure and function following transcatheter ASD closure in adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective observational cohort study included 112 patients aged 15\u201368 years who underwent transcatheter ASD closure. Comprehensive echocardiography was performed pre\u2010procedure and at 1 and 6 months postprocedure. Parameters assessed included right and left ventricular dimensions, atrial volumes, right ventricular systolic pressure (RVSP), pulmonary artery pressure (PAP), tricuspid regurgitation (TR) severity, and right ventricular ejection fraction (RVEF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant reductions in right atrial volume index (RAVI) by 4.5\u2009\u00b1\u20095.19\u2009mL\/m\u00b2, right ventricular internal diameter, RVSP by 6.8\u2009\u00b1\u20099.44\u2009mmHg, PAP decreased by 6.46\u202f\u2009\u00b1\u2009\u202f8.50\u2009mmHg, and TR severity were observed at 6 months (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Left ventricular dimensions and ejection fraction remained stable, indicating preserved left\u2010heart function. RVEF improved in 31% of patients by 6 months. Cardiac rhythm remained unchanged. Notably, reverse remodeling magnitude and timing were independent of baseline ASD size.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Transcatheter ASD closure results in early and sustained right\u2010heart reverse remodeling and pulmonary pressure reduction, without adverse effects on left ventricular function or cardiac rhythm. These consistent benefits, regardless of defect size, support the safety and efficacy of this minimally invasive intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70237","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T04:41:28Z","timestamp":1762749688000},"page":"187-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Short\u2010Term Cardiac Functional Change Following Transcatheter Atrial Septal Defect Closure: A Prospective Echocardiographic Study"],"prefix":"10.1002","volume":"107","author":[{"given":"Zahra","family":"Khajali","sequence":"first","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ata","family":"Firouzi","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6468-6687","authenticated-orcid":false,"given":"Mani","family":"Moayerifar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Healthy Heart Research Center, Heshmat Hospital, School of Medicine Guilan University of Medical Sciences Rasht Iran"},{"name":"Department of Cardiovascular Surgery, Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Baay","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5909-613X","authenticated-orcid":false,"given":"Ehsan","family":"khalilipur","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Elahifar","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9685-7356","authenticated-orcid":false,"given":"Amine Safavi","family":"Rad","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahboobeh","family":"Gholipour","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"},{"name":"Department of Cardiology, Healthy Heart Research Center, Heshmat Hospital, School of Medicine Guilan University of Medical Sciences Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Qasemzade","family":"Eqiani","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Jafari","sequence":"additional","affiliation":[{"name":"Student Research Committee, School of Medicine, Anzali International Campus Guilan University of Medical Sciences Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0587-1350","authenticated-orcid":false,"given":"Behrad","family":"Eftekhari","sequence":"additional","affiliation":[{"name":"Department of Medicine Guilan University of Medical Sciences Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masumeh","family":"Shahrooei","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0772-0403","authenticated-orcid":false,"given":"Maryam Ghanbari","family":"Garekani","sequence":"additional","affiliation":[{"name":"Cardiovascular Intervention Research Center Rajaie Cardiovascular Institute Tehran 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