{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T01:02:29Z","timestamp":1784682149379,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Preprocedural virtual planning of transcatheter aortic valve implantation (TAVI) using FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      may reduce major TAVI complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      (1) To compare morphometric aortic root measurements by FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      and GE software; (2) to validate the accuracy of FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      in predicting post\u2010TAVI paravalvular aortic regurgitation (AR) and new conduction abnormalities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In 106 consecutive TAVI patients, aortic root dimensions essential for prosthesis sizing were measured using both GE software and FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      . FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      predictions were compared with the severity of post\u2010TAVI AR assessed by echocardiography, angiography, invasive hemodynamics, and the development of conduction abnormalities assessed by serial electrocardiography.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bland\u2010Altman analysis revealed smaller annulus perimeter, area and coronary artery ostia heights with FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      compared with GE software, leading to differences in prosthesis sizing in 23% of cases. Predicted AR was significantly higher in patients with moderate versus none\/trace AR on echocardiography (14.3 vs. 2.8\u2009mL\/s,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and angiography (23.6 vs. 4.0\u2009mL\/s,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009), though overlap between adjacent AR grades was observed. Predicted AR did not significantly differ between patients with AR index &lt;\u200925 and \u2265\u200925 (10.2 vs. 5.7\u2009mL\/s,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.079). Contact pressure index was significantly higher in patients with new conduction abnormalities (17.5 vs. 10.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006), despite overlap at patient level.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      generally underestimates aortic root dimensions compared with GE software, affecting prosthesis sizing in a substantial proportion of patients. While predictive at a population level, overlap in parameters predicted by FEops HEARTguide\n                      <jats:sup>TM<\/jats:sup>\n                      is encountered at an individual patient level.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70252","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T12:45:01Z","timestamp":1760445901000},"page":"3747-3756","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Validation of Predictive Procedural Planning Software in a Real\u2010World TAVI Population"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8433-9048","authenticated-orcid":false,"given":"Anne\u2010Sophie","family":"Claes","sequence":"first","affiliation":[{"name":"University of Antwerp Antwerp Belgium"},{"name":"Department of Cardiology Antwerp University Hospital Edegem 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