{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:50:38Z","timestamp":1773103838092,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In\u2010stent restenosis (ISR) remains a major challenge in coronary revascularization, especially in lesions with heavy calcification, where recurrence rates are high. The lack of data on newer treatment options often creates dilemmas for both physicians and patients. Intravascular lithotripsy (IVL) is a relatively new technique that has shown promise in managing calcified ISR. This meta\u2010analysis aims to evaluate the procedural success and clinical outcomes of IVL in this setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA 2020 guidelines, a systematic search was conducted on PubMed, ScienceDirect, and SCOPUS. Studies reporting procedural success and major adverse cardiovascular events (MACE) of IVL for calcified ISR during follow\u2010up were included. The Newcastle\u2010Ottawa Scale was used to assess study quality. Data analysis was performed using RevMan 5.4.0 and SPSS v25.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five studies with a total of 207 patients and 212 lesions treated were analyzed. Acute procedural success was 85% (95% CI 0.76\u20130.91,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200942.0%). At 1\u2010year follow\u2010up, major adverse cardiac events (MACE) included myocardial infarction (MI) in 6% of patients (95% CI 0.02\u20130.16,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200952.5%), target lesion revascularization in 13% (95% CI 0.08\u20130.20,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200945.8%), and cardiac death in 4% (95% CI 0.02\u20130.08,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u20090.0%). The rate of periprocedural MI was 1.5% (95% CI 0.01\u20100.05,\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%), while no reflow phenomenon was 0.5% (95% CI 0.01\u20100.06,\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.0%), with no other procedural complication occured. The overall incidence of MACE was 16% (95% CI 0.07\u20130.33,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200969.8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IVL shows potential as a treatment option for for calcified\u2010ISR, demonstrating high acute procedural success and acceptable 1\u2010year clinical outcomes. The 1\u2010year TLR (13%) and MACE (16%) rates compare favorably with historical data for non\u2010IVL strategies. Further large\u2010scale, controlled studies with longer follow\u2010up are needed to further validate its long\u2010term safety and effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70296","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T10:14:20Z","timestamp":1762510460000},"page":"173-186","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Immediate and Midterm Efficacy and Safety of Intravascular Lithotripsy for Calcified In\u2010Stent Restenosis: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3428-8833","authenticated-orcid":false,"given":"Rifqi Rizkani","family":"Eri","sequence":"first","affiliation":[{"name":"Abdi Waluyo Hospital Jakarta Indonesia"},{"name":"Gatot Soebroto Army Central Hospital Jakarta Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sania","family":"Zahrani","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Indonesia West Java Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasetyo","family":"Andriono","sequence":"additional","affiliation":[{"name":"Abdi Waluyo Hospital Jakarta Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todung D. A.","family":"Silalahi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universitas Prima Indonesia West Java Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.05.017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.11.058"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.10.93"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.10.031"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43044-022-00281-x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29221"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.02.008"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.04.036"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.01.034"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-21-00504"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.03.036"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2023.08.011"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4471-4387-1_38"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.008434"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.09.603"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.02.003"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2023.07.174"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2022.07.023"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2022.06.261"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131274"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.829117"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacasi.2022.11.016"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-021-02259-0"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad026"},{"issue":"2","key":"e_1_2_10_26_1","first-page":"127","article-title":"Drug\u2010Eluting Balloon for Management of Coronary In\u2010Stent Restenosis in a South Asian Population: Experience From a Tertiary\u2010Care Hospital in Pakistan","volume":"33","author":"Ahmed S. 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