{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T04:51:14Z","timestamp":1767761474180,"version":"3.48.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In\u2010stent restenosis (ISR) after drug\u2010eluting stent (DES) implantation remains clinically relevant in patients with elevated body mass index (BMI). This study aimed to develop and internally validate a simple nomogram for ISR risk after DES in patients with overweight\/obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To develop and internally validate a simple nomogram for predicting in\u2010stent restenosis (ISR) after drug\u2010eluting stent (DES) implantation in patients with overweight or obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single\u2010center retrospective cohort (2018\u20132023) of adults with BMI\u2009\u2265\u200925\u2009kg\/m\u00b2 receiving first DES was analyzed. ISR was defined as \u2265\u200950% diameter stenosis within the stent or within 5\u2009mm of its edges on follow\u2010up angiography. Patients were randomly split 70\/30 into training and validation cohorts. Four clinically prespecified predictors\u2014smoking, diabetes, total stent length, and stent diameter\u2014were entered into multivariable logistic regression to derive a nomogram. Performance was evaluated by AUC, calibration plots with Hosmer\u2013Lemeshow testing, bootstrapping, and decision curve analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 468 high BMI patients were included, among whom 49 experienced ISR. Multivariate logistic regression analysis revealed smoking, diabetes, stent total length, and stent diameter as factors associated with ISR occurrence. The Nomogram model demonstrated strong predictive performance in both the training and validation sets, with C\u2010index values of 0.753 and 0.729, respectively. Calibration curves and decision curve analysis further confirmed the reliability and clinical utility of the model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A four\u2010variable nomogram provides pragmatic ISR risk stratification after DES in patients with overweight\/obesity, supporting individualized follow\u2010up and secondary prevention. External validation and prospective evaluation are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70300","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T05:49:50Z","timestamp":1762321790000},"page":"103-111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Internal Validation of a Four\u2010Predictor Nomogram for In\u2010Stent Restenosis After Drug\u2010Eluting Stent Implantation in Patients With Overweight\/Obesity"],"prefix":"10.1002","volume":"107","author":[{"given":"Guo\u2010Biao","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine The First People's Hospital of Fuzhou City Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da\u2010Qing","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Fifth People's Hospital of Ganzhou Ganzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0504-0594","authenticated-orcid":false,"given":"Song\u2010Mao","family":"Ouyang","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit The First Affiliated Hospital of Gannan Medical University Ganzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1614362"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2021.104754"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1171-x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/1028415X.2020.1758888"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-023-00847-5"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13340"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz388"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915925"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-014-0297-x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-021-02255-4"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv511"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28572"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S357250"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.837330"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207508"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.026492"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/6210204"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.1003322"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-23-00107"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29211"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268757"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-24-1362"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e34077"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc3201.094225"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2019.11.035"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1227\/neu.0000000000002798"},{"issue":"4","key":"e_1_2_11_28_1","first-page":"1002","article-title":"Association of Smoking With Restenosis and Major Adverse Cardiac Events After Coronary Stenting: A Meta\u2010Analysis","volume":"31","author":"Hu R. 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