{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:21:16Z","timestamp":1773098476848,"version":"3.50.1"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coronary artery calcification (CAC) is frequently observed in the ageing population, affecting 90% of men and 67% of women, and poses significant challenges during percutaneous coronary interventions (PCIs). CAC impedes stent passage, compromises drug delivery, and limits stent expansion, contributing to decreased PCI efficacy and heightened risks of complications such as restenosis, thrombosis, and procedural issues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The study aims to evaluate the real\u2010world clinical outcomes of orbital atherectomy (OA) in patients with severe CAC undergoing PCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed 20 patients (14 males and 6 females) who underwent OA at a single center. OA employed a 1.25\u2009mm diamond\u2010coated burr at 80,000 and 120,00\u2009rpm in selected cases. Baseline characteristics, lesion specifics, and procedural outcomes, as well as changes in minimal lumen diameter (MLD), minimal lumen area (MLA), and minimal stent area (MSA), were assessed along with procedural complications and adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After OA, a statistically significant increment was observed in MLD and MLA, with mean changes of 2.00\u2009mm and 7.17\u2009mm\u00b2, respectively. The postprocedural MSA was reported as 6.33\u2009\u00b1\u20092.85\u2009mm\u00b2. At 30 days and 6 months after the procedure, only one major adverse cardiac event (MACE), due to stent thrombosis was observed. At 12 months, three MACE (15%) were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OA is a promising intervention for managing severe CAC, enhancing procedural success, optimizing luminal gain, and improving stent delivery and expansion while reducing procedural complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70330","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:49:36Z","timestamp":1764308976000},"page":"547-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real\u2010World Outcomes of Orbital Atherectomy in Managing Severely Calcified Coronary Artery Lesions: A Single\u2010Center Experience"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5363-8952","authenticated-orcid":false,"given":"Sarita","family":"Rao","sequence":"first","affiliation":[{"name":"Department of Cardiology, Cath Lab Apollo Hospitals Indore Madhya Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roshan Rao","family":"K","sequence":"additional","affiliation":[{"name":"Department of Cardiology Apollo Hospitals Indore Madhya Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achukatla","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Apollo Hospitals Indore Madhya Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CP9.0000000000000069"},{"key":"e_1_2_9_3_1","unstructured":"\u201cWorld Heart Report 2023. Confronting the World\u2032s Number One Killer \u201d World Heart Federation 2023 https:\/\/world\u2010heart\u2010federation.org\/wp\u2010content\/uploads\/World\u2010Heart\u2010Report\u20102023.pdf."},{"key":"e_1_2_9_4_1","unstructured":"\u201cNew Study Reveals Latest Data on Global Burden of Cardiovascular Disease \u201d American College of Cardiology December 11 2023 https:\/\/www.acc.org\/About\u2010ACC\/Press\u2010Releases\/2023\/12\/11\/18\/48\/New\u2010Study\u2010Reveals\u2010Latest\u2010Data\u2010on\u2010Global\u2010Burden\u2010of\u2010Cardiovascular\u2010Disease."},{"key":"e_1_2_9_5_1","unstructured":"\u201cCardiovascular Diseases (CVDs) \u201d World Health Organization cited November 6 2024 https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/cardiovascular\u2010diseases\u2010(cvds)."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lansea.2023.100156"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3933.ijam20233565"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscai.2023.101259"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2403093"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12050520"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12237246"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12101638"},{"issue":"12","key":"e_1_2_9_13_1","article-title":"Systematic Review of the Efficacy of Orbital Atherectomy in Improving the Outcome of Percutaneous Corornary Intervention in People With Diabetes","volume":"15","author":"Muoghalu C. 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I.Vidovich \u201cRotational vs. Orbital Atherectomy: How to Choose? [Internet] \u201d Society for Cardiovascular Angiography and Interventions 2020 https:\/\/scai.org\/rotational\u2010vs\u2010orbital\u2010atherectomy\u2010how\u2010choose."},{"issue":"10","key":"e_1_2_9_27_1","article-title":"Current Treatment Modalities for Calcified Coronary Artery Disease: A Review Article Comparing Novel Intravascular Lithotripsy and Traditional Rotational Atherectomy","volume":"12","author":"Kaul A.","year":"2020","journal-title":"Cureus"},{"issue":"4","key":"e_1_2_9_28_1","article-title":"Outcomes of Orbital Atherectomy for the Treatment of Severely Calcified Coronary Artery Lesions","volume":"15","author":"Manasrah N.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007448"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.15420\/icr.2019.17.R1"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12124025"},{"issue":"11","key":"e_1_2_9_32_1","first-page":"440","article-title":"Gender\u2010Based Differences in Outcomes After Orbital Atherectomy for the Treatment of De Novo Severely Calcified Coronary Lesions","volume":"28","author":"Lee M. 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