{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:21:24Z","timestamp":1773098484062,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coronary bifurcation lesions account for 20% of all percutaneous coronary interventions. Acute coronary syndromes involve thrombotic conditions; however, methods for assessing this risk in thrombus\u2010containing bifurcations are unestablished.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aimed to determine whether perfusion balloon dilatation can predict the occurrence of side branch occlusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 38 acute coronary syndrome patients with 65 side branches undergoing percutaneous coronary intervention using a perfusion balloon were enrolled. Based on the side branch flow during perfusion balloon dilatation, the branches were divided into PB\u2010SAFE (perfusion balloon side branch\u2010assisted flow stability, with side branch flow maintained) and not\u2010SAFE (with side branch flow loss) groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The PB\u2010SAFE group did not have cases of side branch occlusion, whereas side branch occlusion occurred in 13 (31.7%) branches in the not\u2010SAFE group. Further, this group was identified as a significant predictor of side branch occlusion (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). In a lesion\u2010level multivariable analysis with per\u2010patient clustering, not\u2010SAFE remained an independent predictor of side branch occlusion (adjusted OR 20.8, 95% CI 4.08\u2212106,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The PB\u2010SAFE, our original predictor of side branch occlusion, can predict patients at risk of side branch occlusion during acute coronary syndrome bifurcation lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70372","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T08:06:43Z","timestamp":1763971603000},"page":"467-476","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predicting Side Branch Occlusion in Acute Coronary Syndrome Using the Perfusion Balloon"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6343-7199","authenticated-orcid":false,"given":"Hiroshi","family":"Abe","sequence":"first","affiliation":[{"name":"Department of Cardiology Juntendo University Urayasu Hospital Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dai","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology Juntendo University Urayasu Hospital Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Cardiology Juntendo University Urayasu Hospital Urayasu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Tomaru","sequence":"additional","affiliation":[{"name":"Department of Cardiology Juntendo University Urayasu Hospital Urayasu 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