{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:20:55Z","timestamp":1773098455606,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Culotte stenting is one of the most preferred techniques in the percutaneous coronary intervention (PCI) of coronary bifurcation lesion (CBL). Therefore, clinical event predictors in culotte stenting are gaining importance. Bifurcation angle (BA) is an important determinant of the clinical outcomes for the PCI of CBL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Our aim in this study was to investigate the impact of BA in culotte stenting technique on cardiovascular outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The OPTIMUM trial was a single\u2010center, observational registry. A total of 1408 PCI procedures were evaluated, and 200 patients were included. Then, patients were divided into two groups according to the BA. 157 patients with BA 70\u00b0 or less were categorized as group 1, while 43 with BA more than 70\u00b0 were categorized as group 2. The primary endpoint of the study was the target lesion failure (TLF) which was a composite endpoint of target vessel myocardial infarction (TVMI), target lesion revascularization (TLR) and cardiac death at 1\u2010 and 3\u2010year follow\u2010up periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The incidence of TLF at 1\u2010year (4 [2.5%]; 4 [9.3%],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.048) and 3\u2010year [14 (8.9%); 10 (23.3%),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008] were significantly lower in patients with BA 70\u00b0 or less compared to patients with BA more than 70\u00b0 that was mainly driven by the TLR at 3\u2010year (10 [6.4%]; 8 [18.6%],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013). The incidence of TVMI (5 [3.2%]; 2 [4.7%],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.648) and cardiac death (4 [2.5%]; 2 [4.7%],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.458) were similar in both groups at 3\u2010year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The wider BA is associated with increased 3\u2010year TLR and TLF in culotte stenting technique.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70390","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T06:38:06Z","timestamp":1764743886000},"page":"683-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Coronary Bifurcation Angle on Cardiovascular Outcomes in Culotte Stenting Technique: The Insights From the OPTIMUM Trial"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2468-2793","authenticated-orcid":false,"given":"Mehmet","family":"Erturk","sequence":"first","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2796-0987","authenticated-orcid":false,"given":"Serkan","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1571-7034","authenticated-orcid":false,"given":"Deniz","family":"Demirci","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2835-7530","authenticated-orcid":false,"given":"Gokhan","family":"Demirci","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2739-4543","authenticated-orcid":false,"given":"Yunus E.","family":"Erata","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2244-3238","authenticated-orcid":false,"given":"Mustafa A.","family":"Yavas","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1692-6417","authenticated-orcid":false,"given":"Irem","family":"Turkmen","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3579-2306","authenticated-orcid":false,"given":"Ahmet Y.","family":"Cizgici","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9112-5754","authenticated-orcid":false,"given":"Serkan","family":"Aslan","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5882-0525","authenticated-orcid":false,"given":"Hicaz Zencirkiran","family":"Agus","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7686-5356","authenticated-orcid":false,"given":"Umit","family":"Bulut","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6517-7278","authenticated-orcid":false,"given":"Ahmet","family":"Guner","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9258-5389","authenticated-orcid":false,"given":"Ahmet A.","family":"Yalcin","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3553-7468","authenticated-orcid":false,"given":"Ali K.","family":"Kalkan","sequence":"additional","affiliation":[{"name":"Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology University of Health Sciences Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00510-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.124.014616"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.03.054"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","unstructured":"Y.Murasato Bench Testing of Coronary Bifurcation Stenting Technique: How Is It Done? Does it Help Technical Decision Making? Moussa ID Colombo A edr. Tips and Tricks in Interventional Therapy of Coronary Bifurcation Lesions. Information Healthcare. 2010; 193\u2013210.","DOI":"10.3109\/9781841847276-10"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-8932(10)70202-5"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCA.0000000000000422"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.11.030"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn512"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-019-1192-2"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.023"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.5543\/tkda.2025.98697"},{"key":"e_1_2_9_13_1","first-page":"457","article-title":"Treatment of Coronary Bifurcation Lesions, Part II: Implanting Two Stents. The 16th Expert Consensus Document of the European Bifurcation Club, Eurointervention: Journal of EuroPCR in Collaboration With the Working Group on Interventional Cardiology of the European Society of Cardiology, Part II: Implanting Two Stents","volume":"18","author":"Lassen J. F.","year":"2022","journal-title":"The 16th Expert Consensus Document of the European Bifurcation Club. 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