{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T05:16:43Z","timestamp":1775107003384,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Young adults undergoing percutaneous coronary intervention (PCI) are often perceived as low risk, yet long\u2010term outcome data in this population are limited. Understanding predictors of adverse events in this group may uncover important targets for improving procedural and postprocedural care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the incidence and predictors of 12\u2010month mortality and major adverse cardiovascular events (MACE) in a contemporary Australian cohort of young patients undergoing PCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed data from the Victorian Cardiac Outcomes Registry (VCOR), a multicenter state\u2010wide PCI registry, including all patients aged 18\u201355 years who underwent PCI between 2014 and 2023. Patients with out\u2010of\u2010hospital cardiac arrest or cardiogenic shock were excluded. The primary outcome was 12\u2010month all\u2010cause mortality; secondary outcomes included in\u2010hospital events and 30\u2010day major adverse cardiovascular events (MACE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 16,410 patients, most were aged 45\u221255 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200913,188\/16,410; 80.4%), and the majority presented with acute coronary syndromes (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200910,792\/16,410; 65.8%). The 12\u2010month mortality was 1.0%, with no difference across age subgroups. Independent predictors for long\u2010term mortality included eGFR \u2264\u200930 (HR 6.99; 95% CI 4.98\u20139.80), left ventricular ejection fraction &lt;\u200935% (HR 5.35; 95% CI 4.01\u20137.13), diabetes (HR 1.65; 95% CI 1.33\u20132.03), and female sex (HR 1.42; 95% CI 1.14\u20131.78). Use of dual antiplatelet therapy at 30 days was lower in those who died (49.4% vs. 88.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Procedural factors such as femoral access and use of bare\u2010metal stents were also more common in this group. Stent thrombosis, stroke, and major bleeding were disproportionately represented among those who died.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although 12\u2010month mortality after PCI in young adults is low, patients with comorbidities such as diabetes, chronic kidney disease, and left ventricular dysfunction experience disproportionately worse outcomes. These findings highlight the need for improved adherence to evidence\u2010based secondary prevention in this high\u2010risk subset.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70434","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T10:55:08Z","timestamp":1768560908000},"page":"1303-1311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes in Young Patients Undergoing Percutaneous Coronary Intervention"],"prefix":"10.1002","volume":"107","author":[{"given":"Isaac","family":"Park","sequence":"first","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7260-5924","authenticated-orcid":false,"given":"Millie","family":"Watkins","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diem","family":"Dinh","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Brennan","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6785-3185","authenticated-orcid":false,"given":"Riley J.","family":"Batchelor","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne Australia"},{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Australia"},{"name":"Department of Cardiology Alfred Health Melbourne 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Cardiology Royal Melbourne Hospital Melbourne Australia"},{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne Australia"},{"name":"School of Public Health and Preventive Medicine Monash University Melbourne Australia"},{"name":"Department of Medicine University of Melbourne Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anoop N.","family":"Koshy","sequence":"additional","affiliation":[{"name":"Department of Cardiology Royal Melbourne Hospital Melbourne Australia"},{"name":"Department of Medicine University of Melbourne Melbourne Australia"},{"name":"Department of Cardiology Austin Health Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"VCOR 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