{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T05:17:51Z","timestamp":1775107071748,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:00:00Z","timestamp":1770508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:00:00Z","timestamp":1770508800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n This study's objective was to investigate the incidence and long\u2010term outcomes of measured (PPM\n M<\/jats:sub>\n ) and predicted (PPM\n P<\/jats:sub>\n ) prosthesis\u2010patient mismatch in patients undergoing valve\u2010in\u2010valve (ViV) transcatheter aortic valve implantation (TAVI).\n <\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n To assess the outcomes of predicted and measured PPM in patients undergoing ViV TAVI.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This retrospective, multicenter analysis included patients who underwent ViV TAVI at the Baylor Scott & White Health\u2010Care System between 2012 and 2021. Effective orifice area (EOA) was measured at discharge using transthoracic echocardiography and indexed to body surface area (EOAi), and predicted EOAi was derived from published reference values according to valve type and size. PPM was classified using standard EOAi cutoff values and subsequently reclassified using obesity\u2010adjusted EOAi thresholds for patients with body mass index\u2009\u2265\u200930\u2009kg\/m\u00b2.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 162 patients treated with ViV\u2010TAVI were analyzed: 64.8% were male, 34% had a BMI\u2009\u2265\u200930kg\/m\u00b2, and the median age was 77 [69.2; 84.0] years. The median STS risk score was 6.3 [3.5; 9.65] %. TAVI was performed trans\u2010femorally in 95.7%, using balloon\u2010expandable (52.5%) and self\u2010expanding (47.5%) devices. The incidence of severe PPMP was significantly lower than that of severe PPMM, both before (14.8% vs. 28.4%,\n p\u2009<\/jats:italic>\n =\u20090.005) and after adjusting for BMI (11.1% vs. 24.7%,\n p\u2009<\/jats:italic>\n =\u20090.002). Both severe PPMP and PPMM predicted high residual pressure gradient (\u2265\u200920mmHg) (\n p\u2009<\/jats:italic>\n =\u20090.004,\n p\u2009<\/jats:italic>\n =\u20090.002, respectively), with no statistical superiority (Delong test,\n p\u2009<\/jats:italic>\n =\u20090.82). Five\u2010year mortality was 52% for PPMM and 51% for PPMP. Severe\u2010PPMM and severe\u2010PPMP were not significantly associated to increased mortality when compared to the absence of PPMM (50% vs. 57% survival; HR 1.76,\n p\u2009<\/jats:italic>\n =\u20090.221) or PPMP (69% vs. 58% survival; HR 0.81,\n p\u2009<\/jats:italic>\n =\u20090.713), respectively.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n In this single healthcare system experience, neither measured PPM nor predicted PPM were predictive of 5\u2010year mortality in patients undergoing ViV\u2010TAVI.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ccd.70493","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T05:58:11Z","timestamp":1770616691000},"page":"1484-1493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Five\u2010Year Outcomes of Measured and Predicted Prosthesis\u2010Patient Mismatch Following Valve\u2010in\u2010Valve Transcatheter Aortic Valve Implantation"],"prefix":"10.1002","volume":"107","author":[{"given":"Karim","family":"Al\u2010Azizi","sequence":"first","affiliation":[{"name":"Department of Cardiology Baylor Scott & White The Heart Hospital Plano Plano Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghadi","family":"Moubarak","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1536-1098","authenticated-orcid":false,"given":"Mohamad Bader","family":"Abo Hajar","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor","family":"Pickering","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cody W.","family":"Dorton","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8984-4354","authenticated-orcid":false,"given":"Kyle A.","family":"McCullough","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Ladner","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Elias","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Parro","sequence":"additional","affiliation":[{"name":"Baylor Scott & White Research Institute Dallas Texas 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