{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T05:15:34Z","timestamp":1775106934638,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n There are limited data on seasonal variations and outcomes in pulmonary embolism (PE).<\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n To understand the seasonal variations in PE outcomes.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n All adult (\u00b318 years) non\u2010elective admissions with a primary diagnosis of PE were identified using the National Inpatient Sample (2016\u20132022) and assessed by the season of admission\u2014spring (March\u2013May), summer (June\u2013August), fall (September\u2013November), and winter (December\u2013February). The primary outcome was in\u2010hospital mortality across the seasons. Secondary outcomes included total hospitalization costs, hospital length of stay, and discharge disposition.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n During the 7\u2010year period, 1,278,754 PE admissions were identified. Spring, summer, fall, and winter had 24.1%, 25.0%, 25.3%, and 25.6% admissions, respectively (\n p<\/jats:italic>\n \u2009<\u20090.001). The baseline and in\u2010hospital characteristics were comparable across cohorts with no significant clinical differences noted. Mechanical thrombectomy rates were highest in fall (spring 2.5%, summer 3.0%, fall 3.5%, winter 2.7%,\n p<\/jats:italic>\n \u2009<\u20090.001), whereas systemic thrombolysis (spring 2.9%, summer 3.0%, fall 2.9%, winter 3.1%,\n p<\/jats:italic>\n \u2009=\u20090.04) was highest in the summer. Use of other therapies were comparable. There was no statistical difference in adjusted in\u2010hospital mortality rates among seasons. There were slight variations in hospitalization costs, length of stay, and discharge dispositions across the four cohorts but were not clinically relevant.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n In this study, there was no significant seasonal variation in in\u2010hospital mortality from PE.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ccd.70520","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T04:05:36Z","timestamp":1770696336000},"page":"1549-1553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Seasons on the Management and Outcomes of Pulmonary Embolism"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4172-3849","authenticated-orcid":false,"given":"Mridul","family":"Bansal","sequence":"first","affiliation":[{"name":"Department of Medicine East Carolina University Brody School of Medicine Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3491-5503","authenticated-orcid":false,"given":"Aryan","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Connecticut School of Medicine Farmington Connecticut USA"},{"name":"Brown University Health Cardiovascular Institute Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghanshyam P. S.","family":"Shantha","sequence":"additional","affiliation":[{"name":"Division of Cardiology East Carolina Heart Institute Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Lynn Morris","sequence":"additional","affiliation":[{"name":"Division of Cardiology East Carolina Heart Institute Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily D.","family":"Missov","sequence":"additional","affiliation":[{"name":"Division of Cardiology East Carolina Heart Institute Greenville North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Dawn Abbott","sequence":"additional","affiliation":[{"name":"Brown University Health Cardiovascular Institute Providence Rhode Island USA"},{"name":"Division of Cardiology, Department of Medicine Warren Alpert Medical School of Brown University Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-8238","authenticated-orcid":false,"given":"Saraschandra","family":"Vallabhajosyula","sequence":"additional","affiliation":[{"name":"Brown University Health Cardiovascular Institute Providence Rhode Island USA"},{"name":"Division of Cardiology, Department of Medicine Warren Alpert Medical School of Brown University Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31814855f2"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2007.12.010"},{"key":"e_1_2_5_4_1","unstructured":"Healthcare Cost and Utilization Project accessed December 13 2025 https:\/\/hcup-us.ahrq.gov\/."},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/circ.148.suppl_1.14344"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-017-0361-1"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/07420520601139755"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2018.370"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)12338-2"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2024-200429"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.10.061"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T03:46:24Z","timestamp":1775101584000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/ccd.70520"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70520","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]},"assertion":[{"value":"2025-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}