{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:08:20Z","timestamp":1778825300568,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The optimal choice between balloon\u2010expandable (BE) and self\u2010expanding (SE) transcatheter heart valves (THVs) in patients with low\u2010flow low\u2010gradient aortic stenosis (LFLG AS) undergoing transcatheter aortic valve replacement (TAVR) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to compare outcomes of BE THVs and SE THVs in patients with LFLG AS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a retrospective, single\u2010institution cohort study of TAVR procedures between 2012 and 2024. Patients with LFLG AS (mean gradient &lt;\u200940\u2009mmHg and ejection fraction &lt;\u200950% or stroke volume index &lt;\u200935\u2009mL\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) were stratified by respective valve type. Patients with prior aortic valve replacement were excluded. Postoperative outcomes were compared between groups. Kaplan\u2212Meier estimates and a Cox regression model were generated for survival. Cumulative incidence curves and a cause\u2010specific cox regression model were generated for heart failure (HF) readmission.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 732 patients identified underwent TAVR for LFLG AS. Of these, 478 (65.3%) received a BE THV and 254 (34.7%) received a SE THV. STS PROM was similar between groups. There was no difference in 30\u2010day mortality between groups. SE THVs had a lower mean gradient but increased rates of paravalvular leak at 30 days post\u2010TAVR. Kaplan\u2212Meier estimates were comparable between groups and there was no significant difference after multivariable analysis (HR 1.15, 95% CI 0.90\u22121.46,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.27). Cumulative incidence estimates of HF readmission were similar between groups, however, BE THV was associated with reduced hazard of HF readmission on multivariable analysis (HR 0.77, 95% CI 0.59\u22120.99,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with LFLG AS undergoing TAVR, BE and SE THVs have comparable midterm survival. BE THVs have a reduced risk of HF readmission on multivariable analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70529","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:18:56Z","timestamp":1772986736000},"page":"1718-1725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Balloon\u2010Expandable Versus Self\u2010Expanding Valves in Low\u2010Flow, Low\u2010Gradient Aortic Stenosis: Does Valve Type Matter?"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9871-1219","authenticated-orcid":false,"given":"Nav","family":"Warraich","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Division of Cardiac Surgery University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Division of Cardiac Surgery University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbad","family":"Sultan","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Division of Cardiac Surgery University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin","family":"Kliner","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA"},{"name":"Department of Medicine, Division of Cardiology University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Serna\u2010Gallegos","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Division of Cardiac 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