{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:47:17Z","timestamp":1790203637207,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter aortic valve (TAV) failure may require redo transcatheter aortic valve replacement (redo\u2010TAVR). The multiple layers of metal after redo\u2010TAVR may jeopardize coronary artery patency and accessibility and result in prosthesis\u2010patient mismatch. Dedicated software may use multi\u2010slice computed tomography (MSCT) imaging to simulate TAV deployment relative to the prior TAV and the individual's anatomy and predict coronary accessibility and TAV expansion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We aimed to validate redo\u2010TAVR simulations created in FEops HEARTguide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter observational study included redo\u2010TAVR patients who had MSCT imaging available at baseline, after index\u2010TAVR and after redo\u2010TAVR. Patient\u2010specific redo\u2010TAVR simulations were created. Simulated valve\u2010to\u2010aorta distances (a proxy for coronary accessibility), neoskirt height, TAV expansion at multiple frame levels, and residual valve area after redo\u2010TAVR were compared to follow\u2010up MSCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 25 patients, HEARTguide simulations of valve\u2010to\u2010coronary (VTC) distance (left VTC 6.0\u2009\u00b1\u20092.2 vs. 6.4\u2009\u00b1\u20092.3\u2009mm, ICC\u2009=\u20090.856,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; right VTC 5.8\u2009\u00b1\u20091.9 vs. 5.6\u2009\u00b1\u20091.9\u2009mm, ICC\u2009=\u20090.740,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) showed good agreement while valve\u2010to\u2010sinotubular\u2010junction (VTSTJ) distance showed moderate agreement with follow\u2010up MSCT (left VTSTJ 2.5\u2009\u00b1\u20091.8 vs. 3.3\u2009\u00b1\u20091.8\u2009mm, ICC\u2009=\u20090.614,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004; right VTSTJ 2.8\u2009\u00b1\u20091.8 vs. 2.9\u2009\u00b1\u20091.2\u2009mm, ICC\u2009=\u20090.613,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). Redo\u2010TAVR frame expansion simulations (mean frame area 434.8\u2009\u00b1\u2009141.6 vs. 401.6\u2009\u00b1\u2009142.9\u2009mm, ICC\u2009=\u20090.930,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; 393.5\u2009\u00b1\u200963.2 vs. 383.1\u2009\u00b1\u200982.5\u2009mm, ICC\u2009=\u20090.822,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, respectively) and simulations of residual valve area after redo\u2010TAVR showed good agreement for self\u2010expanding and balloon\u2010expandable TAV (407.8\u2009\u00b1\u200967.8 vs. 389.6\u2009\u00b1\u200950.4\u2009mm, ICC\u2009=\u20090.837,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; 358.0\u2009\u00b1\u200966.1 vs. 336.1\u2009\u00b1\u200979.9\u2009mm, ICC\u2009=\u20090.823,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this pilot study, MSCT\u2010derived simulations of redo\u2010TAVR provided accurate insights into coronary accessibility, TAV expansion, and residual valve area.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70530","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:37:59Z","timestamp":1773013079000},"page":"1743-1754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Computed Tomography Derived Procedure Simulations for Redo Transcatheter Aortic Valve Replacement"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2124-109X","authenticated-orcid":false,"given":"Mark M. P.","family":"van den Dorpel","sequence":"first","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9674-0278","authenticated-orcid":false,"given":"Ole","family":"de Backer","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9596-558X","authenticated-orcid":false,"given":"Mohamed","family":"Abdel\u2010Wahab","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Beneduce","sequence":"additional","affiliation":[{"name":"Department of Cardiology Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Dumonteil","sequence":"additional","affiliation":[{"name":"Department of Cardiology Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Blackman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Leeds Teaching Hospitals NHS Trust Leeds Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9229-4777","authenticated-orcid":false,"given":"Yannick","family":"Willemen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Dargan","sequence":"additional","affiliation":[{"name":"Department of Cardiology St George's University Hospital NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Cardiology Prince Charles Hospital Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8628-1410","authenticated-orcid":false,"given":"Joost","family":"Daemen","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1273-3612","authenticated-orcid":false,"given":"Lucas Uchoa","family":"de Assis","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"van Niekerk","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Kardys","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Tchetche","sequence":"additional","affiliation":[{"name":"Department of Cardiology Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"De Beule","sequence":"additional","affiliation":[{"name":"FEops Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rutger","family":"Jan Nuis","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Rocatello","sequence":"additional","affiliation":[{"name":"FEops Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nic","family":"Debusschere","sequence":"additional","affiliation":[{"name":"FEops Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Mortier","sequence":"additional","affiliation":[{"name":"FEops Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2732-1205","authenticated-orcid":false,"given":"Nicolas M.","family":"Van Mieghem","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thoraxcenter Erasmus University Medical Center Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.shj.2024.100339"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.05.005"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.120.009496"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-20-00475"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.01.017"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.122.012388"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-01094"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-22-00958"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV11I9A212"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.06.016"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV16I12A176"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.123.013766"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2022.11.023"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-21-01091"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.123.013238"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.067363"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2024.07.009"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2022.07.013"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.931207"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.001"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2024.05.001"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30816"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2018.02.017"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-66899-6"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005344"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt-24-60"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70530","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:19:12Z","timestamp":1778822352000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,23]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ccd.70530"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70530","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,23]]},"assertion":[{"value":"2025-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}