{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:08:25Z","timestamp":1778825305368,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Elliptical annular anatomy has been considered a risk factor for adverse outcomes after TAVI, particularly paravalvular leakage (PVL). Prosthesis oversizing is thought to improve sealing, but the interaction between annular shape and sizing strategy remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the combined impact of annular shape and sizing strategy on procedural success and short\u2010term outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective single\u2010center study, 509 patients undergoing TAVI between January 2021 and December 2024 were analyzed. Ellipticity index (EI) was defined as the ratio of maximum to minimum annular diameter on preprocedural CT. The sizing index (SI) was calculated as prosthesis diameter relative to mean annular diameter. Primary and secondary endpoints were device success and PVL \u2265 mild, PPI, new\u2010onset LBBB, and early safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean EI and SI were 1.27\u2009\u00b1\u20090.10; 15.3% \u00b1 12.4%. Device success was achieved in 89% and was not significantly associated with EI (aOR 0.197, 95% CI 0.013\u20133.309,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.25). Increasing SI was associated with higher device success, although this association did not reach statistical significance (aOR 1.017,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.088). Success rates peaked with moderate oversizing (6%\u201315%; 93%). PVL \u2265 mild occurred in 30% with undersizing and 14% with optimal oversizing but showed no association with EI or SI. Heatmaps showed lower device success when high EI (&gt; 1.32) coincided with suboptimal SI (\u2264 5% or \u2265 25%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Annular ellipticity alone did not predict adverse outcomes. While exploratory analysis suggested reduced device success in patients with both high ellipticity and suboptimal sizing, no significant interaction was identified. Moderate oversizing was associated with the most favorable results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70540","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:12:59Z","timestamp":1773004379000},"page":"1774-1781","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Annular Ellipticity and Sizing Strategy in Transcatheter Aortic Valve Implantation: Independent or Combined Risk Patterns?"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9810-0860","authenticated-orcid":false,"given":"Emre","family":"Polat","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Schemet","sequence":"additional","affiliation":[{"name":"Department of Mathematical Statistics and Artificial Intelligence in Medicine University of Augsburg Augsburg Germany"},{"name":"Center for Advanced Analytics and Predictive Sciences (CAAPS), University of Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0291-4378","authenticated-orcid":false,"given":"Sarah","family":"Friedrich Welz","sequence":"additional","affiliation":[{"name":"Department of Mathematical Statistics and Artificial Intelligence in Medicine University of Augsburg Augsburg Germany"},{"name":"Center for Advanced Analytics and Predictive Sciences (CAAPS), University of Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Amer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Centre Helios Wuppertal University of Witten\/Herdecke Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaldas","family":"Girdauskas","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Owais","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Centre Helios Wuppertal University of Witten\/Herdecke Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.07.003"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.04.003"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25005"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30507"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.01.048"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-00115"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2024.05.034"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.shj.2023.100278"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht051"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rec.2018.06.005"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.109.885152"},{"issue":"4","key":"e_1_2_15_13_1","first-page":"190","article-title":"Relationship of Aortic Annular Eccentricity and Paravalvular Regurgitation Post Transcatheter Aortic Valve Implantation With Corevalve","volume":"25","author":"Wong D. 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