{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:08:28Z","timestamp":1778825308151,"version":"3.51.4"},"reference-count":5,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 31\u2010year\u2010old woman with primary Sj\u00f6gren's syndrome presented with severe pre\u2010capillary pulmonary arterial hypertension (mean pulmonary arterial pressure 51 mmHg, pulmonary vascular resistance 14.7 Wood units) and active renal impairment (24\u2010hour urinary protein 1290 mg). Despite initial immunosuppressive therapy and dual oral PAH\u2010targeted treatment with ambrisentan and tadalafil, she remained at high risk. She subsequently underwent pulmonary artery denervation (PADN) using a 45\u2010mm ablation catheter with 120\u2010second radiofrequency applications at three sites on the main pulmonary artery. At 2\u2010month follow\u2010up, she demonstrated significant symptomatic improvement to WHO functional class I, with a 6\u2010minute walk distance of 320 meters, improved hemodynamics (mean pulmonary arterial pressure 35 mmHg, pulmonary vascular resistance 5.63 Wood units), and a reduced NT\u2010proBNP level of 320 pg\/mL, achieving an intermediate\u2010low risk status according to the 2022 ESC\/ERS guidelines. Renal function also improved (24\u2010hour urinary protein 158 mg). This case suggests that PADN may be an effective adjunctive interventional strategy for refractory autoimmune PAH, even with concurrent renal involvement, facilitating simultaneous cardiopulmonary and renal recovery.<\/jats:p>","DOI":"10.1002\/ccd.70546","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T10:16:36Z","timestamp":1773051396000},"page":"1847-1850","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Artery Denervation for Refractory Sj\u00f6gren's Syndrome\u2010Associated Pulmonary Arterial Hypertension: A Case Report of Combined Hemodynamic and Renal Recovery"],"prefix":"10.1002","volume":"107","author":[{"given":"Jingjing","family":"Hu","sequence":"first","affiliation":[{"name":"Fifth People's Hospital of Chengdu Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-069X","authenticated-orcid":false,"given":"Fengyou","family":"Yao","sequence":"additional","affiliation":[{"name":"Fifth People's Hospital of Chengdu Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kev223"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/710401"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.14842"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2023.101776"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-23-00349"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70546","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70546","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:19:36Z","timestamp":1778822376000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,9]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ccd.70546"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70546","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,9]]},"assertion":[{"value":"2025-12-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}