{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T11:11:00Z","timestamp":1780312260733,"version":"3.54.0"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It is unclear whether preprocedural anemia independently affects outcomes after elective PCI in men with stable CAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Using the TriNetX US Collaborative Network, we identified adult men undergoing first\u2010time elective PCI (2016\u20132024) and compared those with hemoglobin\u2009&lt;\u200913\u2009g\/dL (1\u20137 days pre\u2010PCI) to non\u2010anemic controls. Propensity\u2010score matching produced two balanced cohorts (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091424). Outcomes at 7 days, 30 days, 6 months, and 12 months were analyzed with univariate and multivariable Cox models. Residual confounding was assessed with falsification endpoints and E\u2010values, and multiplicity with Bonferroni and Benjamini\u2013Hochberg adjustments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After propensity\u2010score matching, 7\u2010day outcomes were similar between groups. At 30 days, anemia was associated with higher risks of AKI (HR 1.92; 95% CI 1.35\u20132.72) and major bleeding (HR 2.49; 95% CI 1.48\u20134.19); however, the 30\u2010day association with all\u2010cause hospitalization (HR 1.32; 95% CI 1.05\u20131.66) did not remain statistically significant after multiplicity adjustment. At 6 months, anemia was linked to higher risks of AKI (HR 2.34; 95% CI 1.84\u20132.97), mortality (HR 2.63; 95% CI 1.63\u20134.26), hospitalization (HR 1.56; 95% CI 1.34\u20131.80), major bleeding (HR 3.28; 95% CI 2.34\u20134.61), and transfusion (HR 5.47; 95% CI 3.31\u20139.06); the association with MACE (HR 1.37; 95% CI 1.10\u20131.70) was sensitive to multiplicity adjustment (significant under false\u2010discovery\u2010rate control but not Bonferroni). At 12 months, anemia remained associated with higher risks of AKI (HR 1.96; 95% CI 1.60\u20132.41), mortality (HR 1.88; 95% CI 1.31\u20132.70), hospitalization (HR 1.41; 95% CI 1.23\u20131.62), major bleeding (HR 2.16; 95% CI 1.66\u20132.81), and transfusion (HR 3.35; 95% CI 2.31\u20134.85); the association with MACE (HR 1.26; 95% CI 1.03\u20131.53) did not persist after multiplicity adjustment. Each 1\u2009g\/dL increase in hemoglobin was associated with lower risks of AKI and transfusion in univariate Cox models, with similar directionality after adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In men undergoing first\u2010time elective PCI for stable CAD, baseline anemia was associated with higher 12\u2010month risks of AKI, major bleeding, transfusion, hospitalization, and death\u2014especially with recent (\u2264\u20091 year) bleeding or transfusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70583","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T04:01:29Z","timestamp":1775188889000},"page":"2198-2213","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Impact of Baseline Anemia on Outcomes After Elective PCI in Men: A US Retrospective Cohort Study"],"prefix":"10.1002","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8300-0262","authenticated-orcid":false,"given":"Abdalhakim","family":"Shubietah","sequence":"first","affiliation":[{"name":"Department of Medicine Advocate Illinois Masonic Medical Center Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-2875","authenticated-orcid":false,"given":"Mohamed S.","family":"Elgendy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Tanta University Tanta Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Saad","family":"Rakab","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Mansoura University Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Medicine Al\u2010Quds University East Jerusalem West Bank Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batoul","family":"Abusalah","sequence":"additional","affiliation":[{"name":"Department of Medicine An\u2010Najah National University Nablus West Bank Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed R.","family":"Murad","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belal Mohamed","family":"Hamed","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza A.","family":"Abdul\u2010Hafez","sequence":"additional","affiliation":[{"name":"Department of Medicine An\u2010Najah National University Nablus West Bank Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2718-8627","authenticated-orcid":false,"given":"Ahmed","family":"Emara","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qutaiba","family":"Qafisheh","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Toledo Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsayed","family":"Balbaa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5122-8200","authenticated-orcid":false,"given":"Ameer","family":"Awashra","sequence":"additional","affiliation":[{"name":"Department of Medicine An\u2010Najah National University Nablus West Bank Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Mansour","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elbataa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdalrahman","family":"Assaassa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thomas Jefferson University Hospital Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1443-7177","authenticated-orcid":false,"given":"Mohammed","family":"Mhanna","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Iowa  Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"R. 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