{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T18:32:46Z","timestamp":1786559566649,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter aortic valve implantation (TAVI) in bicuspid aortic valve (BAV) anatomy remains challenging due to anatomical complexity and limited trial data. New\u2010generation balloon\u2010expandable valves, such as Myval, require further evaluation in this subgroup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To report 1\u2010year VARC\u20103 outcomes following TAVI procedure with the Myval transcatheter heart valve (THV) in BAV anatomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From December 2019 to July 2023, 52 consecutive BAV patients at moderate\u2010to\u2010high surgical risk or deemed unsuitable for surgery underwent TAVI with the Myval THV. Outcomes, assessed per VARC\u20103 definitions, were compared to 217 trileaflet aortic valve (TAV) patients in unmatched and propensity score\u2010matched cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 1 year, BAV and TAV patients showed no significant differences in all\u2010cause mortality (3.9% vs. 10.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.185), cardiac mortality (0% vs. 2.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.587), or stroke (3.9% vs. 2.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.654) regarding an unmatched comparison. In the matched analysis, all\u2010cause mortality and stroke were 3.9% and 1.9%, respectively, with no cardiac deaths. Endocarditis was rare (1.9% vs. 1.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.579); no valve thrombosis occurred. At 1 year, 94% of matched patients were in NYHA class I. Echocardiographic parameters remained stable; no moderate\/severe paravalvular regurgitation was observed in BAV patients. Kaplan\u2013Meier analysis revealed no differences in survival or composite outcomes. Technical and device success rates exceeded 95%; early safety was limited by a high incidence of non\u2010vascular type 2\u20134 bleeding events. Based on the analyses, the relatively high postprocedural PPI rate (unmatched BAV vs. TAV: 34.0% vs. 30.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.429; matched: 34.0% vs. 24.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.274) is more likely attributable to patient\u2010related characteristics rather than device\u2010related complications, and remained unchanged following hospital discharge.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TAVI with the Myval THV in real\u2010world BAV patients is safe and effective with excellent hemodynamic performance at 1 year follow\u2010up. This may reinforce the use of this device in this anatomically complex population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70640","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T09:00:35Z","timestamp":1776934835000},"page":"144-162","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single Centre Experience With the Balloon\u2010Expandable Myval Transcatheter Aortic Valve System in Patients With Bicuspid Anatomy: 1 Year Follow\u2010Up"],"prefix":"10.1002","volume":"108","author":[{"given":"Bal\u00e1zs","family":"Magyari","sequence":"first","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1lint","family":"Kittka","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilona","family":"Goj\u00e1k","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Kasza","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Medical School, University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krist\u00f3f","family":"Sch\u00f6nfeld","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3 Botond","family":"Szap\u00e1ry","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mih\u00e1ly","family":"Simon","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Kiss","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bertalan","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edit","family":"V\u00e1rady","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Medical School, University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Szokodi","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Heart Institute, Medical School University of P\u00e9cs P\u00e9cs 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ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy: Developed by the Task Force on Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology (ESC) With the Special Contribution of the European Heart Rhythm Association (EHRA)","volume":"75","author":"Glikson M.","year":"2022","journal-title":"Revista Espanola De Cardiologia (English ed.)"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.033"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx785"},{"key":"e_1_2_11_16_1","doi-asserted-by":"crossref","unstructured":"J. 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Early Clinical and Haemodynamic Matched Comparison of Balloon\u2010Expandable Valves. 2021.","DOI":"10.1136\/heartjnl-2021-319349"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70640","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70640","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T18:15:23Z","timestamp":1786558523000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,23]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/ccd.70640"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70640","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,23]]},"assertion":[{"value":"2025-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}