{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:57:07Z","timestamp":1785776227511,"version":"3.56.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Whether strut thickness influences clinical outcomes after percutaneous coronary intervention (PCI) for bifurcation lesions remains debated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To compare the safety and efficacy of ultrathin (&lt;\u200970\u2009\u00b5m) drug\u2010eluting stents (DES) with thicker DES in coronary bifurcations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We pooled patient\u2010level data from the ULTRA and BIFURCAT registries. Stents were classified as thick (\u2265\u2009100\u2009\u00b5m), thin (70\u2013100\u2009\u00b5m), or ultrathin (&lt;\u200970\u2009\u00b5m). The primary endpoint was target\u2010lesion revascularization (TLR). Inverse probability of treatment weighting (IPTW) balanced baseline characteristics overall and within procedural subgroups (provisional vs. planned two\u2010stent strategy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 6753 patients (median follow\u2010up 800 days, IQR 400\u2013900), 514 (8%) received thick, 5139 (76%) thin, and 1100 (16%) ultrathin stents. Crude TLR rates were 3.3%, 2.8%, and 1.1%, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). After IPTW adjustment, ultrathin DES significantly reduced TLR compared with thick DES (HR 0.38, 95% CI\u2009=\u20090.16\u20130.89,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03) and with thin DES (HR 0.41, 95% CI 0.21\u20130.81,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). In provisional\u2010stenting cases, TLR risk did not differ across groups (HR: 0.53 vs. thick,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.27; HR: 0.49 vs. thin,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.07). Conversely, in planned two\u2010stent procedures ultrathin DES resulted associated with TLR reduction versus thick DES (HR: 0.21, 95% CI 0.04\u20130.93,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), with a nonsignificant trend for thin DES (HR: 0.31,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.07).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In contemporary bifurcation PCI, ultrathin DES are associated with a clinically and statistically significant reduction in repeat revascularization compared with thicker\u2010strut platforms, a benefit driven predominantly by lesions treated with an upfront two\u2010stent approach.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70669","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:32:47Z","timestamp":1780403567000},"page":"554-563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Strut Thickness for Patients Treated With Percutaneous Revascularization for Coronary Bifurcations: Insights From the BIFURCAT\u2010ULTRA Registry"],"prefix":"10.1002","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5092-7225","authenticated-orcid":false,"given":"Matteo","family":"Michelone","sequence":"first","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6646-9317","authenticated-orcid":false,"given":"Fabrizio","family":"D'Ascenzo","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun\u2010Kyeong","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Keimyung University Dongsan Hospital Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeehoon","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cardiovascular Center Seoul National University Hospital Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-1272","authenticated-orcid":false,"given":"Leonardo","family":"De Luca","sequence":"additional","affiliation":[{"name":"Division of Cardiology Fondazione IRCCS Policlinico San Matteo Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Rino","family":"Cimino","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hong","family":"Choi","sequence":"additional","affiliation":[{"name":"Heart Vascular Stroke Institute, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9233-0821","authenticated-orcid":false,"given":"Gianluca","family":"Di Pietro","sequence":"additional","affiliation":[{"name":"Department of Clinical Internal, Anesthesiology and Cardiovascular Sciences Sapienza University of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Bertello","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Mattesini","sequence":"additional","affiliation":[{"name":"Cardiothoracovascular Department Azienda Ospedaliero\u2010Universitaria Careggi and University of Florence Florence Italy"},{"name":"Department of Experimental and Clinical Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Wanha","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Structural Heart Diseases Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Yeub","family":"Lee","sequence":"additional","affiliation":[{"name":"Heart Vascular Stroke Institute, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0542-0448","authenticated-orcid":false,"given":"Sebastiano","family":"Gili","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino IRCCS Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1386-349X","authenticated-orcid":false,"given":"Hyun Kuk","family":"Kim","sequence":"additional","affiliation":[{"name":"Chosun University Hospital Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Capoccia","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2926-9428","authenticated-orcid":false,"given":"Antonio","family":"Greco","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliero\u2010Universitaria Policlinico \u2018G. Rodolico\u2010San Marco\u2019 University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Iannaccone","sequence":"additional","affiliation":[{"name":"Division of Cardiology, San Giovanni Bosco Hospital ASL Citt\u00e0 di Torino Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u2010Jong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Bucheon Sejong Hospital Bucheon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Cortese","sequence":"additional","affiliation":[{"name":"Harrington Heart &amp; Vascular Institute University Hospitals Cleveland Medical Center Cleveland Ohio USA"},{"name":"DCB Academy Milan Italy"},{"name":"Fondazione Ricerca e Innovazione Cardiovascolare Milano Italy"},{"name":"Consiglio Nazionale delle Ricerche (CNR\u2010IEIIT) Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Bin","family":"Song","sequence":"additional","affiliation":[{"name":"Heart Vascular Stroke Institute, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Capodanno","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliero\u2010Universitaria Policlinico \u2018G. Rodolico\u2010San Marco\u2019 University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon\u2010Cheol","family":"Gwon","sequence":"additional","affiliation":[{"name":"Heart Vascular Stroke Institute, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bruno","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Tuttolomondo","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Parma Parma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bon\u2010Kwon","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cardiovascular Center Seoul National University Hospital Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano Maria","family":"De Ferrari","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3370-5774","authenticated-orcid":false,"given":"Chang\u2010Wook","family":"Nam","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine Keimyung University Dongsan Hospital Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidio","family":"De Filippo","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Department, Division of Cardiology Citt\u00e0 della Salute e della Scienza Hospital Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"10.4244","article-title":"The Basics Flow and Atherosclerosis in Coronary Bifurcations","volume":"6","author":"Giannoglou G. D.","year":"2010","journal-title":"EuroIntervention Supplement"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.31254"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.03.038"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2021.06.031"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21314"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-726X(200003)49:3<274::AID-CCD11>3.0.CO;2-N"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2007.118679"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-E-22-00018"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29071"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad342"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.034456"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28667"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.003210"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2019.1776"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.07.040"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000001037"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31920-1"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32467-X"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32249-3"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-15-0264"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.07.760"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.23.2816"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.10.903"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.09.028"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30696"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2024.01.018"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-24-00160"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-24-00471"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.03.012"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab283"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-23-00211"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa543"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.04.056"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70669","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70669","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70669","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:33:02Z","timestamp":1785774782000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/ccd.70669"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70669","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]},"assertion":[{"value":"2025-12-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}