{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:57:25Z","timestamp":1785776245047,"version":"3.56.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter aortic valve replacement (TAVR) has become an established therapy for severe aortic stenosis (AS) across all surgical risk categories. However, data from Latin America remain scarce, particularly using standardized outcome definitions such as those from the Valve Academic Research Consortium\u20103 (VARC\u20103).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To describe baseline characteristics, technical and device success, and early clinical outcomes over a 12\u2010year period at a single established TAVR program in Colombia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective observational case series of consecutive patients with severe symptomatic AS who underwent TAVR between January 2012 and December 2023. Data were collected from institutional databases and electronic health records. Outcomes were defined according to VARC\u20103 criteria and assessed at 30 days. Procedural success and secondary endpoints were analyzed using the Wilson score method for 95% confidence intervals to account for the sample size. Exploratory temporal trend and multivariable logistic regression analyses were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 134 patients were included (median age 80 years; 52.2% female). Technical success was achieved in 95.5%, and device success at 30 days in 81.3%. Thirty\u2010day mortality was 7.4%; acute kidney injury (19.4%), permanent pacemaker implantation (18.7%), and vascular complications (12.7%) were the most common adverse events. In an exploratory multivariable model, diabetes mellitus was associated with increased 30\u2010day mortality (AOR 1.25, 95% CI 1.07\u20132.41;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021), although this finding is limited by the low absolute number of events and should be interpreted with caution.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this 12\u2010year single\u2010center experience, TAVR demonstrated high technical and device success with complication rates comparable to international benchmarks. These findings support the feasibility and safety of TAVR in a Latin American setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70697","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:12:45Z","timestamp":1781237565000},"page":"602-609","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety and Device Success of Transcatheter Aortic Valve Replacement: A 12\u2010Year Single\u2010Center VARC\u20103 Report"],"prefix":"10.1002","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2694-2712","authenticated-orcid":false,"given":"Juan David","family":"Rojas\u2010Perdomo","sequence":"first","affiliation":[{"name":"Department of Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Uribe\u2010D\u00edaz","sequence":"additional","affiliation":[{"name":"Department of Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar Fernando","family":"Hurtado\u2010Ord\u00f3\u00f1ez","sequence":"additional","affiliation":[{"name":"Department of Hemodynamics and Interventional Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Jaramillo\u2010Villegas","sequence":"additional","affiliation":[{"name":"Department of Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Fuentes\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Perez\u2010Garzon","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Extracorporeal Life Support Unit, Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4613-1703","authenticated-orcid":false,"given":"Henry","family":"Robayo\u2010Amortegui","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Extracorporeal Life Support Unit, Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"},{"name":"School of Medicine Universidad de La Sabana Ch\u00eda Cundinamarca Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernan","family":"Mendoza\u2010Beltran","sequence":"additional","affiliation":[{"name":"Department of Cardiology. Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"1","article-title":"Aortic Stenosis: A Review on Acquired Pathogenesis and Ominous Combination With Diabetes Mellitus","volume":"75","author":"Wal P.","year":"2023","journal-title":"Egyptian Heart Journal [Internet]"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac803"},{"issue":"8","key":"e_1_2_12_4_1","article-title":"Transcatheter Aortic Valve Replacement Programs: Clinical Outcomes and Developments","volume":"9","author":"Kumar V.","year":"2020","journal-title":"Journal of the American Heart Association [Internet]"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000047200.36165.B8"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400590"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1700456"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816885"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab395"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000923?download"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.02.038"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2019.04.016"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-018-00786-8"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.11.013"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12010343"},{"issue":"3","key":"e_1_2_12_21_1","first-page":"1","article-title":"VARC\u20103 Defined Outcome of Valve\u2010in\u2010Valve Transcatheter Aortic Valve Implantation in Stentless Compared with Stented Aortic Bioprostheses","volume":"1","author":"Steul J. 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