{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:20:01Z","timestamp":1788268801242,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T00:00:00Z","timestamp":1782000000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In left atrial appendage closure (LAAC) using newer\u2010generation WATCHMAN FLX\/FLX Pro devices, managing borderline\u2010sized LAA within overlapping zones is common, but optimal device sizing strategies remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To compare clinical outcomes and device\u2010related complications between smaller and larger device sizing strategies for borderline\u2010sized LAA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective study evaluated 91 patients undergoing newer\u2010generation WATCHMAN implantation for borderline\u2010sized LAA between September 2021 and June 2024. Follow\u2010up imaging (transesophageal echocardiography and\/or cardiac computed tomography angiography) was performed 45\u2010120 days post\u2010LAAC, and one\u2010year clinical outcomes were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients were divided into smaller (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200936) and larger (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200955) device groups. The composite primary endpoint (cardiovascular mortality and ischemic stroke) was similar between groups (8.3% vs. 3.6%; hazard ratio [HR], 0.372; 95% CI: 0.074\u20132.650,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.334). However, the secondary efficacy endpoint\u2010peridevice leak (PDL) \u232a3 mm and\/or device\u2010related thrombus (DRT)\u2010was significantly higher in the smaller device group at initial follow\u2010up, even after covariate adjustment (13.9% vs. 1.8%; HR, 0.091; 95% CI: 0.009\u20130.887,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039). Similar findings were observed at one year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For borderline\u2010sized LAA treated with newer\u2010generation WATCHMAN devices, smaller and larger sizing strategies yielded similar one\u2010year clinical outcomes. However, the larger device strategy showed a lower incidence of PDL &gt;3 mm and\/or DRT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70706","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T04:55:42Z","timestamp":1782104142000},"page":"743-751","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Different Device Sizing Strategies Using the Newer\u2010Generation WATCHMAN Devices for Closure of Borderline\u2010Sized Left Atrial Appendage"],"prefix":"10.1002","volume":"108","author":[{"given":"Motoki","family":"Fukutomi","sequence":"first","affiliation":[{"name":"Department of Cardiology Kawasaki Saiwai Hospital Kawasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kawasaki Saiwai Hospital Kawasaki 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.15192"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.04.025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.021"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.050117"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.026295"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2408308"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.122.012183"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacasi.2025.11.015"},{"issue":"1","key":"e_1_2_10_10_1","first-page":"4","article-title":"Percutaneous Left Atrial Appendage Occlusion: The Munich Consensus Document on Definitions, Endpoints, and Data Collection Requirements for Clinical Studies","volume":"19","author":"Tzikas A.","year":"2017","journal-title":"Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.01.039"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.057859"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2024.01.310"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"1","article-title":"Delayed Pericardial Effusion Following Left Atrial Appendage Closure: A 5\u2010Year Single\u2010Center Experience","volume":"35","author":"Mogalapalli A.","year":"2023","journal-title":"Journal of Invasive 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