{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T08:00:36Z","timestamp":1785225636990,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Impella is increasingly used as mechanical circulatory support (MCS) during high\u2010risk percutaneous coronary interventions (HR\u2010PCI). Registry\u2010based data provide insights into the efficacy and safety of Impella\u2010assisted HR\u2010PCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We aimed to evaluate 1\u2010year outcomes of Impella\u2010assisted HR\u2010PCI compared to HR\u2010PCI without MCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred and thirty\u2010eight patients undergoing Impella\u2010assisted PCI, included in the IMPELLA\u2010PL registry, were propensity score\u2010matched with controls from the retrospective CardioSilesia registry who underwent HR\u2010PCI without MCS. Study endpoints included 1\u2010year post\u2010discharge all\u2010cause mortality, myocardial infarction (MI), stroke, rehospitalization for heart failure (HF), and repeat coronary revascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Clinical and angiographic characteristics were comparable in both groups, with higher rates of dyslipidemia (78.3% vs. 37.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), chronic kidney disease (39.9% vs. 16.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and peripheral artery disease (34.1% vs. 8.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) in the IMPELLA\u2010PL cohort. Intravascular ultrasound was more frequently used in the Impella\u2010supported patients (44.2% vs. 25.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), while staged revascularization was more common among controls (30.4% vs. 15.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). At 1 year, rates of post\u2010discharge all\u2010cause mortality, stroke, and repeat coronary revascularization were similar in both groups. MI was less frequent in the IMPELLA\u2010PL cohort (1.4% vs. 10.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), alongside a trend toward lower incidence of rehospitalizations for HF (9.4% vs. 18.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.055).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite an unfavorable cardiovascular risk profile, patients who underwent Impella\u2010assisted HR\u2010PCI had similar 1\u2010year post\u2010discharge survival, with a lower rate of MI, compared to propensity score\u2010matched controls who underwent HR\u2010PCI without MCS. Impella may improve HR\u2010PCI outcomes in selected patients, but further randomized controlled trials are required to confirm this finding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70749","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:18:41Z","timestamp":1785223121000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["One\u2010Year Outcomes of High\u2010Risk Percutaneous Coronary Interventions With Versus Without Mechanical Circulatory Support: Propensity Score\u2010Matched Analysis"],"prefix":"10.1002","author":[{"given":"Aleksandra","family":"G\u0105secka","sequence":"first","affiliation":[{"name":"1st Chair and Department of Cardiology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadiusz","family":"Pietrasik","sequence":"additional","affiliation":[{"name":"1st Chair and Department of Cardiology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Paw\u0142owski","sequence":"additional","affiliation":[{"name":"National Medical Institute of the Ministry of the Interior and Administration Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2405-8982","authenticated-orcid":false,"given":"Jakub Michal","family":"Zimodro","sequence":"additional","affiliation":[{"name":"1st Chair and Department of Cardiology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cie\u015bla","sequence":"additional","affiliation":[{"name":"Department of Science and New Technologies Silesian Center for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7504-7506","authenticated-orcid":false,"given":"Jerzy","family":"Sacha","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital in Opole Opole Poland"},{"name":"Faculty of Physical Education and Physiotherapy Opole University of Technology Opole Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Grygier","sequence":"additional","affiliation":[{"name":"1st Department of Cardiology Poznan University of Medical Sciences Poznan Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Kochman","sequence":"additional","affiliation":[{"name":"1st Chair and Department of Cardiology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateusz","family":"Tajstra","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology, School of Medical Sciences in Zabrze Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Dyrbu\u015b","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology, School of Medical Sciences in Zabrze Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Wojakowski","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Structural Heart Diseases Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6907-2799","authenticated-orcid":false,"given":"Katarzyna","family":"Mizia\u2010Stec","sequence":"additional","affiliation":[{"name":"1st Department of Cardiology, School of Medicine in Katowice Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"\u015awi\u0105tkowski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Congenital Heart Disease and Electrotherapy, Silesian Center for Heart Diseases Medical University of Silesia Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Francuz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Congenital Heart Disease and Electrotherapy, Silesian Center for Heart Diseases Medical University of Silesia Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zbigniew","family":"Kalarus","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Congenital Heart Disease and Electrotherapy, Silesian Center for Heart Diseases Medical University of Silesia Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2031-822X","authenticated-orcid":false,"given":"Grzegorz","family":"Smolka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Health Sciences in Katowice Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"G\u0105sior","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology, School of Medical Sciences in Zabrze Medical University of Silesia Katowice Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"issue":"3","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"e149","DOI":"10.4244\/EIJ-D-24-00386","article-title":"Mechanical Circulatory Support for Complex, High\u2010Risk Percutaneous Coronary Intervention","volume":"21","author":"Ferro E. 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W.","year":"2022","journal-title":"American Heart Journal"},{"issue":"5","key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/ehjacc\/zuab015","article-title":"Joint EAPCI\/ACVC Expert Consensus Document on Percutaneous Ventricular Assist Devices","volume":"10","author":"Chieffo A.","year":"2021","journal-title":"European Heart Journal. Acute Cardiovascular Care"},{"issue":"36","key":"e_1_2_9_12_1","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.1093\/eurheartj\/ehae177","article-title":"2024 ESC Guidelines for the Management of Chronic Coronary Syndromes","volume":"45","author":"Vrints C.","year":"2024","journal-title":"European Heart Journal"},{"issue":"3","key":"e_1_2_9_13_1","first-page":"18","article-title":"2021 ACC\/AHA\/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"145","author":"Lawton J. 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W.","year":"2018","journal-title":"American Heart Journal"},{"issue":"4","key":"e_1_2_9_18_1","doi-asserted-by":"crossref","DOI":"10.1093\/ehjopen\/oeac041","article-title":"Mechanical Circulatory Support Devices for Elective Percutaneous Coronary Interventions: Novel Insights From the Japanese Nationwide J\u2010PCI Registry","volume":"2","author":"Muramatsu T.","year":"2022","journal-title":"European Heart Journal Open"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ijcard.2019.05.065","article-title":"Clinical Expert Consensus Document on the Use of Percutaneous Left Ventricular Assist Support Devices During Complex High\u2010Risk Indicated PCI: Italian Society of Interventional Cardiology Working Group Endorsed by Spanish and Portuguese Interventional Cardiology Societies","volume":"293","author":"Chieffo A.","year":"2019","journal-title":"International Journal of Cardiology"},{"issue":"2","key":"e_1_2_9_20_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4244\/AIJ-D-22-00021","article-title":"Clinical Expert Consensus Document on the Use of Percutaneous Left Ventricular Assist Devices During Complex High\u2010Risk PCI in India Using a Standardised Algorithm","volume":"8","author":"Tayal R.","year":"2022","journal-title":"AsiaIntervention"},{"key":"e_1_2_9_21_1","unstructured":"\u201cThe PROTECT\u2010IV Trial\u201d accessed September 13 2025 https:\/\/clinicaltrials.gov\/study\/NCT04763200."},{"issue":"18","key":"e_1_2_9_22_1","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1056\/NEJMoa2515704","article-title":"Left Ventricular Unloading in High\u2010Risk Percutaneous Coronary Intervention","volume":"394","author":"Perera D.","year":"2026","journal-title":"New England Journal of Medicine"},{"issue":"6","key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.33963\/v.phj.104840","article-title":"Rationale and Design of the Administrative Data and Electronic Medical Records\u2010Based Registry: The Cardiology Scientific Network of the Medical University of Silesia (CardioSilesia)","volume":"83","author":"G\u0105sior M.","year":"2025","journal-title":"Polish Heart Journal"},{"issue":"11","key":"e_1_2_9_24_1","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.33963\/v.kp.97218","article-title":"Multicenter Registry of Impella\u2010Assisted High\u2010Risk Percutaneous Coronary Interventions and Cardiogenic Shock in Poland (IMPELLA\u2010PL)","volume":"81","author":"Pietrasik A.","year":"2023","journal-title":"Kardiologia Polska"},{"issue":"3","key":"e_1_2_9_25_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/MCA.0000000000000824","article-title":"Six Months Follow\u2010Up of Protected High\u2010Risk Percutaneous Coronary Intervention With the Microaxial Impella Pump: Results From the German Impella Registry","volume":"31","author":"Baumann S.","year":"2020","journal-title":"Coronary Artery Disease"},{"key":"e_1_2_9_26_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.carrev.2025.06.003","article-title":"Procedural Characteristics and Outcomes of Patients Undergoing Impella\u2010Assisted High\u2010Risk Percutaneous Coronary Interventions in the IMPELLA\u2010PL Registry","volume":"81","author":"G\u0105secka A.","year":"2025","journal-title":"Cardiovascular Revascularization Medicine: Including Molecular Interventions"},{"issue":"22","key":"e_1_2_9_27_1","first-page":"2431","article-title":"Impact of Intravascular Ultrasound on Long\u2010Term Clinical Outcomes in Patients With Acute Myocardial Infarction","volume":"14","author":"Choi I. 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J.","year":"2022","journal-title":"American Journal of Cardiology"},{"issue":"6","key":"e_1_2_9_30_1","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1002\/ccd.28400","article-title":"Impella Support and Acute Kidney Injury During High\u2010Risk Percutaneous Coronary Intervention: The Global cVAD Renal Protection Study","volume":"95","author":"Flaherty M. P.","year":"2020","journal-title":"Catheterization and Cardiovascular Interventions"},{"issue":"1","key":"e_1_2_9_31_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/ccd.28931","article-title":"Outcomes of Impella\u2010Supported High\u2010Risk Nonemergent Percutaneous Coronary Intervention in a Large Single\u2010Center Registry","volume":"97","author":"Azzalini L.","year":"2021","journal-title":"Catheterization and Cardiovascular Interventions"},{"key":"e_1_2_9_32_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.amjcard.2021.07.014","article-title":"High\u2010Risk Percutaneous Coronary Intervention of Native Coronary Arteries Without Mechanical Circulatory Support in Acute Coronary Syndrome Without Cardiogenic Shock","volume":"158","author":"Khalid N.","year":"2021","journal-title":"American Journal of Cardiology"},{"issue":"1","key":"e_1_2_9_33_1","article-title":"Association Between Standardized Management Algorithm and Outcomes of Patients Undergoing High\u2010Risk Percutaneous Coronary Interventions Included in the IMPELLA\u2010PL Registry","volume":"135","author":"G\u0105secka A.","year":"2025","journal-title":"Polish Archives of Internal Medicine"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70749","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70749","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70749","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:18:46Z","timestamp":1785223126000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":32,"alternative-id":["10.1002\/ccd.70749"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70749","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,28]]},"assertion":[{"value":"2025-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ccd.70749"}}