{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:15:41Z","timestamp":1788920141034,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent trials demonstrated that tricuspid transcatheter edge\u2010to\u2010edge repair (T\u2010TEER) is particularly effective for symptoms and quality of life improvement. However, its effect on prognosis is still unclear. Moreover, the applicability of trials inclusion\/exclusion criteria has not been investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aim of the present study is to investigate the applicability of TRILUMINATE and Tri.Fr trials inclusion and exclusion criteria on real\u2010world patients from TRIVALVE registry, and to evaluate their effects on outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients undergoing T\u2010TEER were selected from the TRIVALVE registry and, according to inclusion and exclusion criteria, divided in four groups: TRILUMINATE eligible versus ineligible and Tri.Fr eligible versus ineligible patients. TRILUMINATE and Tri.Fr analysis were conducted separately.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From a total of 664 patients of the TRIVALVE registry, 520 and 519 were included in the TRILUMINATE and Tri.Fr analysis, respectively. In particular, 240 patients (46%) met the TRILUMINATE criteria and 260 (50%) those of Tri.Fr. Baseline characteristics were significantly different between trials' eligible and ineligible patients. TRILUMINATE\u2010eligible patients showed significant lower mortality\/rehospitalization compared to ineligible ones (12% vs. 25%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.028), as well as Tri.Fr\u2010eligible versus ineligible ones (15% vs. 22%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with TR undergoing T\u2010TEER, inclusion and exclusion criteria of TRILUMINATE and Tri.Fr are applicable to around half of real\u2010world patients. Patients matching trials criteria have lower mortality\/rehospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70763","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T17:27:34Z","timestamp":1784654854000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes Stratified by Adapted Inclusion Criteria After Transcatheter Tricuspid Edge\u2010to\u2010Edge Repair"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6302-0135","authenticated-orcid":false,"given":"Giulio","family":"Russo","sequence":"first","affiliation":[{"name":"Department of Biomedicine and Prevention, Cardiology Unit, Policlinico Tor Vergata University of Rome  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pedicino","sequence":"additional","affiliation":[{"name":"Polo Cardiovascolare Fondazione Policlinico Universitario A 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