{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:19:31Z","timestamp":1788261571138,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Percutaneous closure of femoral arterial access is a critical step in transcatheter aortic valve implantation (TAVI). A hybrid strategy combining a suture\u2010based device (Perclose ProStyle) and a collagen\u2010based device (Angio\u2010Seal) has emerged as an alternative to the conventional double Perclose ProStyle technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The objective of the study is to compare femoral vascular complications between a hybrid strategy (1 Perclose ProStyle+ 1 Angio\u2010Seal) and a non\u2010hybrid strategy (2 Perclose ProStyle) in a large single\u2010center experience.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective, single\u2010center, non\u2010randomized study included 633 consecutive patients who underwent transfemoral TAVI at Timone University Hospital (Marseille, France) between November 2024 and March 2026. The choice of closure strategy was left to the operator's discretion. The primary endpoint was the occurrence of any femoral vascular complication (classified according to VARC\u20103 criteria).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 273 patients underwent hybrid closure, and 360 underwent non\u2010hybrid closure. The overall rate of vascular complications was 4.9% (31\/633), with no significant difference between groups (hybrid 4.8% vs. non\u2010hybrid 5.0%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000). There were no differences in major VARC\u20103 complications (2.2% vs. 1.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000) or minor complications (2.6% vs. 3.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.899). In univariate analysis, preprocedural dual antiplatelet therapy was the main predictor of overall complications, hematoma, pseudoaneurysm, and minor VARC\u20103 complications. Dialysis was associated with major VARC\u20103 complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The hybrid closure strategy (1 Perclose ProStyle + 1 Angio\u2010Seal) demonstrates a vascular safety profile comparable to the conventional strategy (2 Perclose ProStyle) in transfemoral TAVI. Preprocedural antithrombotic therapy, rather than the closure device strategy, appears to be the main determinant of vascular complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70840","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:01:11Z","timestamp":1788260471000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Two Percutaneous Femoral Closure Strategies During Transcatheter Aortic Valve Implantation"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1063-0142","authenticated-orcid":false,"given":"Thomas","family":"Roussel","sequence":"first","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6371-0363","authenticated-orcid":false,"given":"J\u00e9r\u00e9my","family":"Boyer","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7478-2370","authenticated-orcid":false,"given":"Julien","family":"Polo","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadrien","family":"Pichene","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Rahmani","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mence","family":"Bassez","sequence":"additional","affiliation":[{"name":"Cardiology Department CH Toulon Toulon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Quillot","sequence":"additional","affiliation":[{"name":"Service de cardiologie Centre Hospitalier Henri Duffaut Avignon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Dabry","sequence":"additional","affiliation":[{"name":"Service de cardiologie Centre hospitalier du Pays d'Aix Aix\u2010en\u2010Provence France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Vaillier","sequence":"additional","affiliation":[{"name":"Centre Hospitalier D'Ajaccio Ajaccio France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Morera","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Chirurgie Cardiaque CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Jaussaud","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Chirurgie Cardiaque CHU Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Deharo","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"},{"name":"Inserm Inra, C2VN, Aix\u2010Marseille universite\u0301 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0493-5500","authenticated-orcid":false,"given":"Thomas","family":"Cuisset","sequence":"additional","affiliation":[{"name":"De\u0301partement de cardiologie CHU Timone Marseille France"},{"name":"Inserm Inra, C2VN, Aix\u2010Marseille universite\u0301 Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"issue":"44","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.1093\/eurheartj\/ehaf194","article-title":"2025 ESC\/EACTS Guidelines for the Management of Valvular Heart Disease","volume":"46","author":"Praz F.","year":"2025","journal-title":"European Heart Journal"},{"issue":"23","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1001\/jama.2024.16477","article-title":"Calcific Aortic Stenosis: A Review","volume":"332","author":"Otto C. 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