{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T06:06:20Z","timestamp":1788933980040,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ventricular arrhythmias (VA) after percutaneous pulmonary valve implantation (PPVI) have been mainly reported with balloon\u2010expandable valves. Data on VA following self\u2010expandable valves, particularly the Pulsta valve, remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the incidence, clinical characteristics, and predictors of clinically significant VA after Pulsta valve implantation in patients with native right ventricular outflow tract (RVOT) disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 129 consecutive patients who underwent PPVI with the Pulsta valve. All patients received continuous telemetry monitoring until discharge. Clinically significant VA was defined as VA requiring antiarrhythmic therapy. Clinical, electrocardiographic, RVOT morphological, and valve\u2010related variables were analyzed using univariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age at PPVI was 27 years (interquartile range, 22.0\u201336.0). Over a median follow\u2010up of 3.3 years, any VA occurred in 42 patients (32.6%), predominantly transient premature ventricular complexes (PVCs; 16.3%) or non\u2010sustained ventricular tachycardia (VT; 16.3%). Among patients with non\u2010sustained VT, antiarrhythmic therapy was required in 5 patients (3.9%), with only 2 patients (1.6%) remaining on medication at discharge. No sustained VT, hemodynamic instability, or persistent arrhythmia requiring long\u2010term therapy was observed. Proximal RVOT implantation was the strongest predictor of VA (odds ratio 5.74, 95% confidence interval 1.08\u201330.57 vs. mid\/distal RVOT,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039). Other clinical, electrocardiographic, anatomical, and valve\u2010related factors were not associated with VA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with native RVOT disease treated with self\u2010expandable Pulsta valve, clinically significant VA was rare, and most VAs were benign and self\u2010limited. Pulsta valve implantation at proximal RVOT was the key determinant of VA risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70859","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:09:37Z","timestamp":1788930577000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Characteristics and Determinants of Ventricular Arrhythmias After Self\u2010Expandable Pulsta Valve Implantation in the Native Right Ventricular Outflow Tract"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5933-1010","authenticated-orcid":false,"given":"Woo Young","family":"Park","sequence":"first","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7880-280X","authenticated-orcid":false,"given":"Gi Beom","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3071-2661","authenticated-orcid":false,"given":"Sang Yun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0529-869X","authenticated-orcid":false,"given":"Mi Kyoung","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-2762","authenticated-orcid":false,"given":"Seung Min","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0096-7364","authenticated-orcid":false,"given":"Susan Taejung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7393-810X","authenticated-orcid":false,"given":"Duck Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2134-151X","authenticated-orcid":false,"given":"Eun Jung","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University Children's Hospital, Seoul National University College of Medicine Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jscai.2022.100452","article-title":"Transcatheter Pulmonary Valve Replacement: A Review of Current Valve Technologies","volume":"1","author":"Patel N. D.","year":"2022","journal-title":"Journal of the Society for Cardiovascular Angiography & Interventions"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"e689","DOI":"10.1161\/CIR.0000000000001291","article-title":"Long\u2010Term Management of Right Ventricular Outflow Tract Dysfunction in Repaired Tetralogy of Fallot: A Scientific Statement From the American Heart Association","volume":"150","author":"Geva T.","year":"2024","journal-title":"Circulation"},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1002\/ccd.30393","article-title":"Ventricular Arrhythmias Following Transcatheter Pulmonary Valve Replacement With the Harmony TPV25 Device","volume":"100","author":"Taylor A.","year":"2022","journal-title":"Catheterization and Cardiovascular Interventions"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/ccd.30560","article-title":"Ventricular Arrhythmias Following Balloon\u2010Expandable Transcatheter Pulmonary Valve Replacement in the Native Right Ventricular Outflow Tract","volume":"101","author":"Barfuss S. B.","year":"2023","journal-title":"Catheterization and Cardiovascular Interventions"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1002\/ccd.27454","article-title":"Ventricular Arrhythmias Immediately Following Transcatheter Pulmonary Valve Implantation: A Cause for Concern?","volume":"91","author":"Simmons M. A.","year":"2018","journal-title":"Catheterization and Cardiovascular Interventions"},{"key":"e_1_2_11_7_1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.21037\/tp.2019.04.02","article-title":"Percutaneous Pulmonary Valve Implantation (PPVI) in Non\u2010Obstructive Right Ventricular Outflow Tract: Limitations and Mid\u2010Term Outcomes","volume":"8","author":"Esmaeili A.","year":"2019","journal-title":"Translational Pediatrics"},{"key":"e_1_2_11_8_1","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1007\/s00246-022-02881-5","article-title":"Ventricular Arrhythmias and Sudden Death Following Percutaneous Pulmonary Valve Implantation in Pediatric Patients","volume":"43","author":"Veillette P.\u2010O.","year":"2022","journal-title":"Pediatric Cardiology"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"446","article-title":"Ventricular Arrhythmias After Self\u2010Expanding Transcatheter Pulmonary Valve Replacement","volume":"12","author":"Armstrong A. K.","year":"2026","journal-title":"JACC: Clinical Electrophysiology"},{"key":"e_1_2_11_10_1","article-title":"Early Outcomes of Self\u2010Expandable Versus Balloon\u2010Expandable Valves for Managing Dysfunctional Right Ventricular Outflow Tracts","volume":"19","author":"Haddad R. N.","year":"2026","journal-title":"Circulation: Cardiovascular Interventions"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29865"},{"key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1080\/10976640601187596","article-title":"Variations in Right Ventricular Outflow Tract Morphology Following Repair of Congenital Heart Disease: Implications for Percutaneous Pulmonary Valve Implantation","volume":"9","author":"Schievano S.","year":"2007","journal-title":"Journal of Cardiovascular Magnetic Resonance"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30968"},{"key":"e_1_2_11_14_1","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2025.1586134","article-title":"Quantitative Comparisons of Pulmonary Artery Hemodynamics Before and After Pulsta Valve Implantation in Patients With Tetralogy of Fallot Using Computational Fluid Dynamics","volume":"12","author":"Baek S. M.","year":"2025","journal-title":"Frontiers in Cardiovascular Medicine"},{"key":"e_1_2_11_15_1","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1136\/heartjnl-2017-312769","article-title":"Ventricular Arrhythmia Burden After Transcatheter Versus Surgical Pulmonary Valve Replacement","volume":"104","author":"Wadia S. K.","year":"2018","journal-title":"Heart"},{"key":"e_1_2_11_16_1","article-title":"Successful Feasibility Human Trial of a New Self\u2010Expandable Percutaneous Pulmonary Valve (Pulsta Valve) Implantation Using Knitted Nitinol Wire Backbone and Trileaflet \u03b1\u2010Gal\u2010Free Porcine Pericardial Valve in the Native Right Ventricular Outflow Tract","volume":"11","author":"Kim G. B.","year":"2018","journal-title":"Circulation: Cardiovascular Interventions"},{"key":"e_1_2_11_17_1","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/j.jacc.2024.02.010","article-title":"Early Outcomes From a Multicenter Transcatheter Self\u2010Expanding Pulmonary Valve Replacement Registry","volume":"83","author":"Goldstein B. H.","year":"2024","journal-title":"Journal of the American College of Cardiology"},{"key":"e_1_2_11_18_1","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.jcin.2024.12.031","article-title":"Transcatheter Pulmonary Valve Implantation Using Self\u2010Expandable Percutaneous Pulmonary Valve System: 3\u2010Year CE Study Results","volume":"18","author":"Qureshi S. A.","year":"2025","journal-title":"JACC Cardiovascular Interventions"},{"key":"e_1_2_11_19_1","article-title":"Extended Rhythm Monitoring to Assess for Ventricular Arrhythmias After Transcatheter Pulmonary Valve Replacement With the Harmony Valve","volume":"18","author":"Yang J. K.","year":"2025","journal-title":"Circulation: Cardiovascular Interventions"},{"key":"e_1_2_11_20_1","doi-asserted-by":"crossref","DOI":"10.1093\/icvts\/ivad027","article-title":"Commentary: The Ideal Patch Material for Congenital Cardiac Surgery: One Ring to Rule Them All?","volume":"36","author":"Marathe S. P.","year":"2023","journal-title":"Interdisciplinary Cardiovascular and Thoracic Surgery"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70859","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70859","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:09:40Z","timestamp":1788930580000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,8]]},"references-count":19,"alternative-id":["10.1002\/ccd.70859"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70859","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,8]]},"assertion":[{"value":"2026-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ccd.70859"}}