{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:01:21Z","timestamp":1790233281937,"version":"4.1.0"},"reference-count":6,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Iodinated contrast remains a key component of percutaneous coronary intervention, yet it poses a significant risk for contrast\u2010associated acute kidney injury (CA\u2010AKI), particularly in patients with chronic kidney disease (CKD). This review summarizes the evidence, procedural workflow with stepwise approach including clinical implications of ultra\u2010low\u2010contrast PCI (ULC\u2010PCI). We reviewed recent literature describing strategies for contrast reduction, imaging and physiology\u2010guided PCI, and subsequent clinical outcomes. ULC\u2010PCI incorporates techniques such as intravascular imaging (IVUS\/OCT), fractional flow reserve (FFR\/iFR), and dynamic coronary roadmap imaging to safely reduce contrast exposure while maintaining procedural quality. It, thus, represents a paradigm shift toward a safer, precision\u2010guided revascularization. Broader implementation requires structured training in this aspect and further outcome validation.<\/jats:p>","DOI":"10.1002\/ccd.70876","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:12:18Z","timestamp":1790230338000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rethinking Percutaneous Coronary Intervention: The Era of Ultra\u2010Low\u2010Contrast Intervention"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8580-2252","authenticated-orcid":false,"given":"Vasavdatta","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Cardiology BL Kapur Max Super Speciality Hospital New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"S11","article-title":"Contrast\u2010Induced Nephropathy: Definition, Epidemiology, and Patients at Risk","volume":"69","author":"Mehran R.","year":"2006","journal-title":"Proc Contrast\u2010Induc Nephrop Consens Panel"},{"issue":"1","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1523-1755.2005.00377.x","article-title":"Pathophysiology of Contrast Medium\u2013Induced Nephropathy","volume":"68","author":"Persson P. B.","year":"2005","journal-title":"Kidney International"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.15420\/icr.2022.32"},{"issue":"4","key":"e_1_2_8_5_1","first-page":"409","article-title":"Ultra\u2010Low\u2010Contrast PCI","volume":"18","author":"Shabbir A.","year":"2025","journal-title":"JACC: Cardiovascular Interventions"},{"key":"e_1_2_8_6_1","unstructured":"Z. A.Ali. \u201cUltra\u2010Low Contrast Imaging and PCI \u201d (2022)."},{"issue":"3","key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.ihj.2022.04.005","article-title":"The Principles of Ultra\u2010Low Contrast Percutaneous Coronary Intervention","volume":"74","author":"Ezhumalai B.","year":"2022","journal-title":"Indian Heart Journal"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70876","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70876","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70876","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:12:20Z","timestamp":1790230340000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":6,"alternative-id":["10.1002\/ccd.70876"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70876","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]},"assertion":[{"value":"2026-07-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ccd.70876"}}