{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:06:37Z","timestamp":1790251597712,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary cardiac angiosarcoma (PCAS) is an extremely rare and highly aggressive malignant tumor, accounting for ~30% of primary cardiac sarcomas. It predominantly arises in the right atrium with non\u2010specific symptoms, leading to frequent misdiagnosis as myxomas or thrombi. Cases with an 8\u2010year insidious course are exceptionally rare and diagnostically challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 54\u2010year\u2010old female with 8\u2010year intermittent chest tightness acutely worsened for 1 day was evaluated. Diagnostic workup included transthoracic echocardiography (TTE), computed tomography (CT), and laboratory tests. The patient underwent surgical resection under cardiopulmonary bypass, followed by histopathological confirmation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Initial TTE suggested right atrial thrombus, while repeat TTE favored myxoma. CT confirmed a large right atrial mass with moderate pericardial effusion; multiple small pulmonary nodules were assessed as low\u2010risk lesions with no evidence of distant metastasis. Intraoperatively, a 5.0\u2009\u00d7\u20096.0\u2009cm mass was densely adherent to the right atrial wall. Histopathology and immunohistochemistry (CD31+, CD34+, Factor VIII+, Ki\u201067 40%) confirmed angiosarcoma. The patient recovered uneventfully and was referred for adjuvant chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PCAS has an insidious course and is easily misdiagnosed by conventional imaging. Early complete surgical resection remains the mainstay of treatment. A high index of suspicion for malignancy is essential in all patients with right atrial masses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70910","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:02:40Z","timestamp":1789999360000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Primary Cardiac Angiosarcoma of the Right Atrium Initially Misdiagnosed as Myxoma"],"prefix":"10.1002","author":[{"given":"Yi","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Ultrasound Wuhan Asia General Hospital, School of Medicine, University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8171-6637","authenticated-orcid":false,"given":"Huiying","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Wuhan Asia General Hospital, School of Medicine, University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1333-7752","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Wuhan Asia General Hospital, School of Medicine, University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9400-9062","authenticated-orcid":false,"given":"Xiaojing","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Wuhan Asia General Hospital, School of Medicine, University of Science and Technology Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/hearts5030028"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-024-02555-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2024.09.006"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.230126"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1279177"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70910","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70910","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:28:12Z","timestamp":1790249292000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":5,"alternative-id":["10.1002\/ccd.70910"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70910","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"assertion":[{"value":"2026-07-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ccd.70910"}}