{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T05:45:41Z","timestamp":1792561541836,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Frailty is highly prevalent among elderly patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI) and is associated with adverse clinical outcomes and impaired health\u2010related quality of life. However, different frailty assessment tools vary in their conceptual frameworks, assessment domains, and predictive performance, and their applicability in elderly PCI populations remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To compare four commonly used frailty assessment tools, including the Frailty Phenotype (FP), FRAIL scale, Tilburg Frailty Indicator (TFI), and Frailty Index (FI), and to investigate their associations with quality of life in elderly patients with CHD undergoing PCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study included 244 elderly patients with CHD undergoing PCI at a tertiary hospital in Shanghai from August to December 2024. Frailty was assessed using the Frailty Phenotype (FP), FRAIL scale, Tilburg Frailty Indicator (TFI), and Frailty Index (FI), and quality of life using the 12\u2010Item Short Form Health Survey (SF\u201012). Agreement was evaluated using the Kappa statistic. Associations with physical component summary (PCS) and mental component summary (MCS) scores were assessed using correlation and multivariable linear regression, while discriminatory performance was examined using receiver operating characteristic (ROC) and Bayesian discriminant analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean PCS and MCS scores were 40.08\u2009\u00b1\u200911.23 and 52.30\u2009\u00b1\u20097.82, respectively. Frailty prevalence was 40.6% by FP, 8.6% by FRAIL, 28.3% by TFI, and 22.1% by FI. Agreement was fair to moderate (Kappa = 0.242\u20130.496). Higher frailty scores were independently associated with lower PCS and MCS after adjustment for age, sex, education, smoking, and comorbidity burden. FP and FI showed comparable discrimination for PCS, whereas TFI had the highest AUC for MCS. Classification accuracy was highest for FP in PCS and TFI in MCS (both 79.51%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Frailty was consistently associated with poorer quality of life. FP and FI performed similarly for physical health, whereas TFI showed the most favorable performance for mental health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70936","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T05:36:54Z","timestamp":1792561014000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Application of Four Frailty Assessment Tools in Elderly Patients With Coronary Heart Disease PCI and Its Relationship With Quality of Life"],"prefix":"10.1002","author":[{"given":"Meixun","family":"Huang","sequence":"first","affiliation":[{"name":"School of Medicine Tongji University Shanghai China"},{"name":"Cardiology Department Shanghai Pudong New Area People's Hospital Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0886-1214","authenticated-orcid":false,"given":"Chunyan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Nursing Department, Shanghai East Hospital, School of Medicine Tongji University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Xu","sequence":"additional","affiliation":[{"name":"Cardiology Department, Shanghai East Hospital, School of Medicine Tongji University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lang","family":"Liu","sequence":"additional","affiliation":[{"name":"Center of Gallbladder Disease, Shanghai East Hospital, School of Medicine Tongji University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yating","family":"Wu","sequence":"additional","affiliation":[{"name":"Nursing Department, Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohuan","family":"Qin","sequence":"additional","affiliation":[{"name":"Nursing Department, Shanghai East Hospital, School of Medicine Tongji University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176586","article-title":"The Role of Hydrogen in the Prevention and Treatment of Coronary Atherosclerotic Heart Disease","volume":"972","author":"Chen Y.","year":"2024","journal-title":"European Journal of Pharmacology"},{"issue":"5","key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1093\/ageing\/afi146","article-title":"What Would Make a Definition of Frailty Successful?","volume":"34","author":"Rockwood K.","year":"2005","journal-title":"Age and Ageing"},{"issue":"6","key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/j.1532-5415.2006.00745.x","article-title":"Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary From the American Geriatrics Society\/National Institute on Aging Research Conference on Frailty in Older Adults","volume":"54","author":"Walston J.","year":"2006","journal-title":"Journal of the American Geriatrics Society"},{"issue":"4","key":"e_1_2_11_5_1","first-page":"635","article-title":"Frailty and Bone Health in European Men","volume":"46","author":"Cook M. 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