{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:47:03Z","timestamp":1792043223344,"version":"4.4.0"},"reference-count":43,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>To estimate the cumulative incidence of short\u2010term complications across different transcatheter heart valve (THV) prostheses used for transcatheter aortic valve replacement (TAVR). We performed a systematic review and meta\u2010analysis in accordance with PRISMA and a prospectively registered PROSPERO protocol. Observational studies published from 2002 through May 2024 that included patients with severe aortic stenosis undergoing predominantly transfemoral TAVR and reported prosthesis\u2010specific complications were eligible. Although the original protocol intended to evaluate both short\u2010 and long\u2010term complications, long\u2010term outcomes were too sparse and inconsistently reported for robust pooled analyses; therefore, the present analysis focuses on short\u2010term complications. Pooled cumulative incidences were calculated using random\u2010effects models. We included 242 studies comprising 181,187 patients. SAPIEN 3 had the lowest incidence of moderate\u2010to\u2010severe paravalvular leak (PVL) (1.04%, 95% CI 0.69\u20131.55) and stroke (1.87%, 95% CI 1.64\u20132.14), whereas ACURATE neo2 had the lowest incidence of permanent pacemaker implantation (PPI) (7.7%, 95% CI 5.82\u201310.11). Evolut PRO and SAPIEN 3 showed among the lowest rates of major vascular complications (3.56%, 95% CI 2.77\u20134.57 and 3.87%, 95% CI 3.22\u20134.66, respectively) and major or life\u2010threatening bleeding (2.96%, 95% CI 2.09\u20134.17 and 4.8%, 95% CI 4.04\u20135.69, respectively). Short\u2010term complications have decreased with newer\u2010generation THV prostheses. PVL remains more frequent with self\u2010expanding valves, whereas PPI is the most frequent complication and is generally less frequent with balloon\u2010expandable valves and ACURATE neo2. Stroke rates have changed little across newer generations, and annular rupture, coronary artery obstruction, and valve embolization remain rare (&lt;\u20091%).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70944","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:06:02Z","timestamp":1792040762000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Short\u2010Term Complications of Transcatheter Aortic Valve Replacement: A Systematic Review and Meta\u2010Analysis (PROLONG\u2010TAVR)"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1881-9471","authenticated-orcid":false,"given":"Mauricio","family":"Castillo\u2010Perez","sequence":"first","affiliation":[{"name":"Tecnologico de Monterrey Escuela de Medicina y Ciencias de la Salud Monterrey Nuevo Leon 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Medicina Vascular TecSalud, Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey San Pedro Garza Garcia Nuevo Leon Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6586-1993","authenticated-orcid":false,"given":"Paola","family":"Guti\u00e9rrez\u2010Gallegos","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey Escuela de Medicina y Ciencias de la Salud Monterrey Nuevo Leon Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2846-100X","authenticated-orcid":false,"given":"Maria J.","family":"Cabada\u2010Garcia","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey Escuela de Medicina y Ciencias de la Salud Monterrey Nuevo Leon 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