{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T04:13:52Z","timestamp":1764476032511,"version":"3.46.0"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T00:00:00Z","timestamp":1523923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title>\n                  <jats:p>\n                    Delayed hemolytic transfusion reactions (\n                    <jats:styled-content style=\"fixed-case\">DHTR<\/jats:styled-content>\n                    s) occur secondary to slow, mild IgG\u2010mediated processes against minor red blood cell antigens. Herein, we report the case of a rapidly fatal alloimmune anti\u2010c IgM\u2010mediated hemolysis, a rare, previously undescribed, pathophysiologic scenario. Early recognition of such phenomena can expedite supportive measures and optimize patient outcomes.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.1534","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T05:08:47Z","timestamp":1523941727000},"page":"1090-1093","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fatal massive hemolysis caused by immunoglobulin M anti\u2010c antibody in a patient with newly diagnosed B\u2010cell acute lymphoblastic leukemia: a case report"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2155-0939","authenticated-orcid":false,"given":"Carlos","family":"Galvez","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulrahman","family":"Abutaleb","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wade T.","family":"Iams","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul F.","family":"Lindholm","sequence":"additional","affiliation":[{"name":"Department of Pathology Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hau C.","family":"Kwaan","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology Northwestern University Feinberg School of Medicine Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,17]]},"reference":[{"volume-title":"Harrison's principles of internal medicine, 19e","year":"2015","author":"Dzieczkowski J. 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