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Included in this case is a discussion of the development of functional hyposplenism, a rarely reported complication, limitation of <jats:styled-content style=\"fixed-case\">ADAMTS<\/jats:styled-content>\u201013 in diagnosis, and the use of platelet transfusion.<\/jats:p>","DOI":"10.1002\/ccr3.202","type":"journal-article","created":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T14:16:14Z","timestamp":1430835374000},"page":"521-526","source":"Crossref","is-referenced-by-count":6,"title":["Coagulopathy and functional hyposplenism during an episode of thrombotic thrombocytopenic purpura in a HgbS\/<i>\u03b2<\/i><sup>+<\/sup>\u2010thalassemia patient"],"prefix":"10.1002","volume":"3","author":[{"given":"Andrew J.","family":"Gangemi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Drexel University College of Medicine\/Hahnemann University Hospital 245\u00a0N. 15th Street Mail Stop 427 Philadelphia Pennsylvania 19102"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter V.","family":"Pickens","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department Medicine Abington Memorial Hospital 1200 Old York Road Abington Pennsylvania 19001"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp053024"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050558"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-003-0715-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1076029608323804"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23126"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23455"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198708000-00016"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.02082.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199411000-00025"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922809338314"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198810000-00027"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1081\/HEM-120016371"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1997.tb04759.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-012-1647-3"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH08-10-0677"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20653"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-01-0193"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2013.01.024"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2013.05.007"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1076029609352661"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1182\/asheducation-2007.1.91","article-title":"Hypercoagulability in sickle cell disease: new approaches to an old problem","volume":"2007","author":"Ataga K. 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