{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:42:21Z","timestamp":1747147341275,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T00:00:00Z","timestamp":1613088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>DS\u2010ALL has a higher rate of relapse and treatment\u2010related mortality. The newer immunotherapies are potentially better options. Relapsed ALL with positive MRD has a poor prognosis. Transient long\u2010term remission after ALL relapse due to partial chemotherapy combined severe infection is rare.<\/jats:p>","DOI":"10.1002\/ccr3.3678","type":"journal-article","created":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T14:10:08Z","timestamp":1613311808000},"page":"1118-1122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8935-0626","authenticated-orcid":false,"given":"Zhongbo","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children\u2019s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen A.","family":"VanHeyst","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children\u2019s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4418-4919","authenticated-orcid":false,"given":"Jignesh","family":"Dalal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children\u2019s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Hackney","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children\u2019s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1400972"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2014.09.006"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085554"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62002-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12348"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-06-509463"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000000906"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/08880010801938132"},{"issue":"1","key":"e_1_2_8_10_1","first-page":"115","article-title":"Spontaneous remission of acute lymphoblastic leukemia: A case report","volume":"15","author":"Hores T","year":"2018","journal-title":"Oncol Lett"},{"key":"e_1_2_8_11_1","first-page":"1259759","article-title":"Spontaneous Remission in an Older Patient with Relapsed FLT3 ITD Mutant AML","volume":"2016","author":"Vachhani P","year":"2016","journal-title":"Case Rep Hematol"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-881961"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.18.02037"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12442"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70580-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.1915"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-07-453480"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(99)00078-8"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.5315\/wjh.v3.i3.49"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30003-1"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2000.02027.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-235291"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06337.x"},{"issue":"3","key":"e_1_2_8_24_1","first-page":"166","article-title":"Treatment of relapsed\/refractory acute lymphoblastic leukemia","volume":"17","author":"Paul S","year":"2019","journal-title":"Clin Adv Hematol Oncol"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195305)6:3<591::AID-CNCR2820060317>3.0.CO;2-M"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000000648"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90739-4"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1994.tb06761.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.14740\/jh606"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2014.970545"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.3678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.3678","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.3678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T03:43:43Z","timestamp":1693626223000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.3678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,12]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1002\/ccr3.3678"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.3678","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2021,2,12]]},"assertion":[{"value":"2020-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}