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We suggest that the already described vaccine\u2010induced upregulation of Th1 response may play a relevant role in LP reactivation, through an increase in inflammatory cytokines involved in the pathogenesis of LP. Interestingly, LP has already been associated with vaccinations and viral infections including COVID\u201019 disease. However, the exact mechanism underlying LP (re)activation after Pfizer\u2010BiotNtech COVID\u201019 vaccination is still widely unknown and needs to be further investigated.<\/jats:p>","DOI":"10.1002\/ccr3.5092","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T14:45:57Z","timestamp":1638888357000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Lichen planus flare following COVID\u201019 vaccination: A case report"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6373-8801","authenticated-orcid":false,"given":"Astrid","family":"Herzum","sequence":"first","affiliation":[{"name":"Department of Dermatology Di.S.Sal San Martino Polyclinic Hospital IRCCS University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Burlando","sequence":"additional","affiliation":[{"name":"Department of 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