{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T14:46:22Z","timestamp":1774017982930,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Calcium\u2010channel blockers (CCBs) are widely used in people and animals. Overdose can result in cardiovascular collapse and death. Hyperinsulinemia\/euglycemia therapy (HIET) and intralipid therapy (ILT) are reported treatment options in people. This is the first report describing HIET and ILT as treatments for amlodipine toxicosis in a cat.<\/jats:p>","DOI":"10.1002\/ccr3.5175","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T16:03:33Z","timestamp":1638893013000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hyperinsulinemia\/euglycemia and intravenous lipid emulsion therapy for the management of severe amlodipine toxicosis in a cat"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9597-9597","authenticated-orcid":false,"given":"Audrey E.","family":"Tinsman","sequence":"first","affiliation":[{"name":"BluePearl Specialty\u00a0+\u00a0Emergency Pet Hospital New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3532-4879","authenticated-orcid":false,"given":"Tara J.","family":"Bellis","sequence":"additional","affiliation":[{"name":"Emergency &amp; Critical Care Garden State Veterinary Services Iselin NJ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2018.06.002"},{"key":"e_1_2_10_3_1","volume-title":"Small Animal Cardiovascular Medicine","author":"Kittleson MD"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2007.00270.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.4.578"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563650.2011.582471"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc4938"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12053"},{"key":"e_1_2_10_9_1","volume-title":"The Merck Veterinary Manual","author":"Kahn CM","year":"2005"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14625"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-0306-7.00158-6"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-198812007-00012"},{"key":"e_1_2_10_13_1","unstructured":"HolderT.Calcium channel blocker toxicosis. 4."},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-018-9445-3"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2008.12.008"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(97)70196-3"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2011.00657.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0960327120964551"},{"issue":"2","key":"e_1_2_10_19_1","first-page":"744","article-title":"Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine","volume":"267","author":"Kline JA","year":"1993","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1022160"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/2008-2231-22-36"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650701285412"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2019.1580372"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2020.1725034"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.234.11.1398"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X16663269"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X18816489"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12631"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.668688"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002087"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-017-9421-3"},{"key":"e_1_2_10_32_1","volume-title":"Textbook of Small Animal Emergency Medicine","year":"2019"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.5175","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.5175","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.5175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T07:55:21Z","timestamp":1693209321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.5175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1002\/ccr3.5175"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.5175","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"2021-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e05175"}}