{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:19:55Z","timestamp":1783127995492,"version":"3.54.6"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The translocation t(8;9)(p22;p24) results in the production of a chimeric <jats:italic>PCM1<\/jats:italic>\u2010<jats:italic>JAK2<\/jats:italic> fusion protein leading to the constitutive activation of the Janus Kinase 2 that renders this disease potentially sensitive to ruxolitinib. Here, we report an interesting case of <jats:italic>PCM1<\/jats:italic>\u2010<jats:italic>JAK2<\/jats:italic>\u00a0myeloproliferative neoplasm evolving in myeloid sarcoma and B precursor ALL.<\/jats:p>","DOI":"10.1002\/ccr3.5212","type":"journal-article","created":{"date-parts":[[2022,1,8]],"date-time":"2022-01-08T04:44:41Z","timestamp":1641617081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sequential allogeneic transplantation and ruxolitinib maintenance for a synchronous <i>PCM1\u2010JAK2<\/i> positive myeloid sarcoma and acute B\u2010lymphoblastic leukemia"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7518-2521","authenticated-orcid":false,"given":"Giuliana","family":"Rizzuto","sequence":"first","affiliation":[{"name":"Hematology and Bone Marrow Transplantation Unit Azienda Socio\u2010Sanitaria Territoriale Papa Giovanni XXIII Bergamo Italy"},{"name":"Department of 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