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Two missense mutations affecting the <jats:italic>TRMPSS6<\/jats:italic> gene were identified, consistent with IRIDA. Subsequent parenteral iron therapy improved clinical and blood parameters.<\/jats:p>","DOI":"10.1002\/ccr3.6401","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T13:23:29Z","timestamp":1665667409000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Double trouble: A case of fraternal twins with iron\u2010refractory iron\u2010deficiency anemia"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3741-5835","authenticated-orcid":false,"given":"Jacques A. 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