{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:55:19Z","timestamp":1787583319614,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a case of sudden sensorineural hearing loss and rapidly progressive facial palsy in a female patient in her 40s with no, apparently, notable past medical or surgical history. Investigations revealed a positive serology for <jats:italic>B.\u00a0burgdoferi<\/jats:italic> and the MRI allowed us to identify suggestive signs of Lyme meningitis with multiple cranial nerve involvement. After diagnosis, the patient was treated with intravenous ceftriaxone with a full recovery of sensorineural deafness and facial palsy. This case report highlights the importance of collecting a complete medical history in all cases of facial palsy and sudden hearing loss while presenting an infrequent clinical presentation of early disseminated Lyme disease with neuroborreliosis.<\/jats:p>","DOI":"10.1002\/ccr3.6412","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T12:00:26Z","timestamp":1665489626000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0236-8728","authenticated-orcid":false,"given":"Letizia","family":"Nitro","sequence":"first","affiliation":[{"name":"Otolaryngology Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Martino","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6942-4109","authenticated-orcid":false,"given":"Emanuela","family":"Fuccillo","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6763-4305","authenticated-orcid":false,"given":"Giovanni","family":"Felisati","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1457-6871","authenticated-orcid":false,"given":"Alberto Maria","family":"Saibene","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812436449"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2019.1689432"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300202"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1041"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2007.01799.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02862.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noz153"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e3181f3bd4a"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/01455613211041235"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2003.09.034"},{"issue":"8","key":"e_1_2_9_12_1","first-page":"e17435","article-title":"Sudden sensorineural hearing loss following the second dose of COVID\u201019 vaccine","volume":"13","author":"Tsetsos N","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.1259"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2022.05.003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.11.007"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200407000-00016"},{"issue":"2","key":"e_1_2_9_17_1","first-page":"1","article-title":"Cochlear and vestibular lesions in capsular otosclerosis as seen in microdissection","volume":"87","author":"Hawkins JE","year":"1978","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10051130"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005813"},{"key":"e_1_2_9_20_1","unstructured":"European Centre for Disease Prevention and Control.Surveillance and disease data. Accessed June 9 2022.https:\/\/www.ecdc.europa.eu\/en\/disease\u2010vectors\/surveillance\u2010and\u2010disease\u2010data\/tick\u2010maps"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199511163332004"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-013-0240-y"},{"key":"e_1_2_9_23_1","first-page":"46","article-title":"Cochlear and vestibular functional study in patients with sudden deafness and Lyme disease","volume":"3","author":"Selmani Z","year":"2014","journal-title":"Int J Oto Head Neck Surg"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51488"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09387-w"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.6412","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T02:02:33Z","timestamp":1692496953000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.6412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/ccr3.6412"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.6412","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"2022-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e6412"}}