{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:08:58Z","timestamp":1772186938858,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T00:00:00Z","timestamp":1667692800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Reactive arthritis is a rare form of spondyloarthropathies occurring after genital or enteric infection. It is most often self\u2010limited but can progress to chronic spondylarthritis. We report the case of a 30\u2010year\u2010old man who presented with acute arthritis occurring 2\u2009months after an episode of urethral discharge. Physical examination revealed polyarthritis, dactylitis, sacroiliac joint involvement, and plantar papulosquamous plaques. The human leukocyte antigen B27 was positive. Detection of\n                    <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                    and\n                    <jats:italic>Gonococcus<\/jats:italic>\n                    in the first catch urine specimen was negative. Hepatitis B and C,\n                    <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                    , human immunodeficiency virus, and syphilis serologic test results were negative. Pelvic magnetic resonance imaging revealed left sacroiliitis. The patient was treated with antibiotics, diclofenac, and sulfasalazine. After 6\u2009months of follow\u2010up, a significant clinical improvement was obtained without remission, suggesting an evolution to chronic spondylarthritis. Diagnosis of Reactive arthritis is difficult since microbiologic examinations are commonly negative. This disease should be considered in patients with rheumatologic manifestations occurring after a urogenital or enteric infection, mainly when associated with skin manifestations and human leukocyte antigen B27.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.6542","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:20:15Z","timestamp":1667780415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cutaneous and rheumatological manifestations of reactive arthritis: A case report"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6889-9687","authenticated-orcid":false,"given":"Maroua","family":"Slouma","sequence":"first","affiliation":[{"name":"Department of Rheumatology Military Hospital  Tunis Tunisia"},{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4852-3479","authenticated-orcid":false,"given":"Siwar","family":"Ben Dhia","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Military Hospital  Tunis Tunisia"},{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7297-0837","authenticated-orcid":false,"given":"Rim","family":"Dhahri","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Military Hospital  Tunis Tunisia"},{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9640-5613","authenticated-orcid":false,"given":"Noureddine","family":"Litaiem","sequence":"additional","affiliation":[{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"},{"name":"Department of Internal Medicine Military Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Metoui","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Military Hospital  Tunis Tunisia"},{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imen","family":"Gharsallah","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Military Hospital  Tunis Tunisia"},{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassem","family":"Louzir","sequence":"additional","affiliation":[{"name":"Tunis El Manar University  Tunis Tunisia"},{"name":"Department of Dermatology Charles Nicolle Hospital  Tunis Tunisia"},{"name":"Department of Internal Medicine Military Hospital  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-018-4022-5"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4997\/jrcpe.2021.319"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X20975915"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"69","article-title":"Spondyloarthropathies: new directions in etiopathogenesis, diagnosis and treatment","volume":"109","author":"Wilson G","year":"2012","journal-title":"Mo Med"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2009.03.010"},{"key":"e_1_2_11_7_1","volume-title":"Reactive Arthritis [Internet]","author":"Cheeti A","year":"2022"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.therap.2019.01.011"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-022-06241-9"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010\u2010022\u201001858\u2010z"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956462414540617"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.02.047"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.5070\/D327754373"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2005.044057"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-021-01018-6"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200004)43:4<720::AID-ANR2>3.0.CO;2-8"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.133645"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.121192"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.9.880"},{"issue":"2","key":"e_1_2_11_20_1","first-page":"104","article-title":"Predictive factors for the evolution of reactive arthritis to ankylosing spondylitis","volume":"41","author":"Banicioiu\u2010Covei S","year":"2015","journal-title":"Curr Health Sci J"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2006.02.003"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.6542","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:16:41Z","timestamp":1764253001000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.6542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1002\/ccr3.6542"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.6542","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"2022-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e6542"}}