{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:44:00Z","timestamp":1790887440982,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T00:00:00Z","timestamp":1667692800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Lymphoblastic lymphoma is a group of non\u2010Hodgkin lymphomas that account for approximately 2% of all lymphomas. This is a report of a case of a young girl presenting with a solitary scalp mass which was resected. Histopathological examination of the mass along with bone marrow analysis revealed primary cutaneous B\u2010cell lymphoblastic lymphoma. A nine\u2010year\u2010old girl presenting with an asymptomatic erythematous, non\u2010tender scalp mass present for 12\u2009months was admitted. Skull and brain were intact and devoid of any pathological findings on computed tomography imaging. Systemic examination also showed no evidence of mass lesion in other parts of the body. The lesion was resected and referred for pathological analysis. Microscopic study revealed heavy diffuse dermal and subcutaneous infiltration of monomorphous medium\u2010sized mononuclear cells, with fine chromatin, scant cytoplasm, and variable nucleoli along with intact epidermis and presence of grenz zone. Tumor cells dissect through the collagen fibers. Extensive mitotic figures and focal infiltration of the skin adnexa are seen. IHC study revealed that TdT, CD79a, CD99, CD45, CD20, and Ki67 markers were positive. According to these findings, a definitive diagnosis of primary cutaneous lymphoblastic lymphoma of B cell type was concluded. The 1\u2010year follow up after necessary treatment revealed normal findings without traces of recurrence. Lymphoblastic lymphomas (LBL) are a neoplasm of immature B cells belonging to the B\u2010(B\u2010LBL) or T\u2010cell lineage (T\u2010LBL) that accounts for approximately 2% of all lymphomas. Lymphoblastic lymphoma (LBL) is similar to acute lymphoblastic leukemia (ALL) and the differentiation between these neoplasms is based upon proportion of involvement of lymphoblasts in bone marrow. It has a higher male to female predominance, higher incidence in older children and younger adults, and a relatively higher frequency of CNS and gonadal involvement. The differential diagnosis is based on immunohistochemistry study of B\u2010cell linage tumor markers. Cutaneous involvement is present in about one third of patients with B\u2010LBL but rarely in patients with ALL.<\/jats:p>","DOI":"10.1002\/ccr3.6553","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T01:11:27Z","timestamp":1667783487000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Primary cutaneous\n                    <scp>B\u2010Cell<\/scp>\n                    lymphoblastic lymphoma presenting with solitary scalp mass in a female child: A case report and review of the literature"],"prefix":"10.1002","volume":"10","author":[{"given":"Fatemeh","family":"Montazer","sequence":"first","affiliation":[{"name":"Pathology Iran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza Sanei","family":"Motlagh","sequence":"additional","affiliation":[{"name":"Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9543-982X","authenticated-orcid":false,"given":"Ramtin","family":"Dastgir","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Tehran Medical Sciences Islamic Azad University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,6]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"354","article-title":"EORTC classification for primary cutaneous lymphomas: a proposal from the cutaneous lymphoma study Group of the European Organization for research and treatment of cancer","volume":"90","author":"Willemze 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