{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T14:34:34Z","timestamp":1782225274071,"version":"3.54.5"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pituitary metastases are rare. Clinical presentation could range from asymptomatic to panhypopituitarism or local symptoms. We present a case report of a 43\u2010year\u2010old male patient with a new onset headache, visual disturbances, and panhypopituitarism. The investigation led to the diagnosis of pituitary metastasis as the first manifestation of underlying lung cancer.<\/jats:p>","DOI":"10.1002\/ccr3.6601","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T06:09:46Z","timestamp":1670825386000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pituitary metastasis as the first manifestation of lung carcinoma"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2911-9270","authenticated-orcid":false,"given":"Sara","family":"Amaral","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Matias","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Bou\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas","family":"Manique","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Palha","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00edsa","family":"Cortez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00eds","family":"Cerqueira","sequence":"additional","affiliation":[{"name":"Department of Neurorradiology Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalila","family":"Forte","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amets","family":"Sagarribay","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Dutra","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Crist\u00f3v\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Pontinha","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Mafra","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy Centro Hospitalar Universit\u00e1rio Lisboa Central, Hospital de Curry Cabral  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Silva\u2010Nunes","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Metabolism Centro Hospitalar Universit\u00e1rio Lisboa Central  Lisbon Portugal"},{"name":"Nova Medical School\/ Faculdade de Ciencias Medicas Universidade Nova de Lisboa  Lisbon Portugal"},{"name":"Health and Technology Research Center (H&amp;TRC), Escola Superior de Tecnologia da Saude de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030395"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2020.01.013"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2017.06.139"},{"key":"e_1_2_11_5_1","first-page":"100080","article-title":"Pituitary metastasis of small cell lung cancer: two case reports","volume":"19","author":"Quintero B","year":"2021","journal-title":"J Clin Transl Endocrinol Case Rep"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197507)36:1<216::AID-CNCR2820360123>3.0.CO;2-E"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02409058"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019616-200201000-00010"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00164"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-014-0552-2"},{"key":"e_1_2_11_11_1","first-page":"17","article-title":"Panhypopituitarism secondary to pituitary metastases","volume":"29","author":"Pinet C","year":"2000","journal-title":"Presse Med"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000022939"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.6601","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:02:59Z","timestamp":1764306179000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.6601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ccr3.6601"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.6601","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"2022-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e6601"}}