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Here, we discuss a diabetic 54\u2010year\u2010old female presented with malignant otitis externa and bilateral facial paresis followed by cervical spondylitis and C1\u2010C2 instability. Skull base osteomyelitis confirmed by clinical presentation, imaging, and laboratory data. Fortunately, she responded well to antibacterial and antifungal therapy. Due to limited data, there is no confirmed standard of treatment for cervical instability secondary to SBO. It seems antibiotic therapy is the mainstay of treatment. In case of poor response to antibiotic therapy, surgical intervention is inevitable. This article introduces the first case of SBO\u2010related AAI successfully managed with conservative treatment.<\/jats:p>","DOI":"10.1002\/ccr3.6744","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:07:57Z","timestamp":1672099677000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A case of atlantoaxial instability following skull base osteomyelitis: Tips for diagnosis and management"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7994-1097","authenticated-orcid":false,"given":"Faramarz","family":"Roohollahi","sequence":"first","affiliation":[{"name":"Neurological Surgery Department, Shariati Hospital Complex Tehran University of Medical Sciences  Tehran 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