{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:38:37Z","timestamp":1783431517437,"version":"3.54.6"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ondansetron is an FDA\u2010approved selective serotonin 5\u2010HT3 receptor commonly indicated as an anti\u2010emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure. We report a case of anaphylactoid reaction with spontaneous coronary vasospasms in response to intravenous ondansetron.<\/jats:p>","DOI":"10.1002\/ccr3.6781","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T23:14:45Z","timestamp":1671750885000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Ondansetron\u2010induced pseudoallergy with non\u2010ischemic myocardial injury: A rare case report of Kounis syndrome"],"prefix":"10.1002","volume":"10","author":[{"given":"Eden","family":"Firew","sequence":"first","affiliation":[{"name":"American Medical Center  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2809-0154","authenticated-orcid":false,"given":"Helen","family":"Huang","sequence":"additional","affiliation":[{"name":"University of Medicine and Health Sciences, Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0279-4636","authenticated-orcid":false,"given":"Ayush","family":"Anand","sequence":"additional","affiliation":[{"name":"B. P. Koirala Institute of Health Sciences  Dharan Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1541-2257","authenticated-orcid":false,"given":"Yonathan Aliye","family":"Asfaw","sequence":"additional","affiliation":[{"name":"Internal Medicine Addis Hiwot Hospital  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charmy","family":"Parikh","sequence":"additional","affiliation":[{"name":"Pramukh Swami Medical College  Karamsad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza Rafique","family":"Khan","sequence":"additional","affiliation":[{"name":"Bahawal Victoria Hospital  Bahawalpur Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199141040-00006"},{"key":"e_1_2_14_3_1","volume-title":"StatPearls","author":"Griddine A","year":"2022"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/106002809102500408"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.18773\/austprescr.2020.011"},{"key":"e_1_2_14_6_1","first-page":"3","article-title":"Pharmacology of ondansetron","volume":"6","author":"Naylor RJ","year":"1992","journal-title":"Eur J Anaesthesiol Suppl"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012775.pub2"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-020-03680-x"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005506.pub5"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2013.780026"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_2_14_12_1","unstructured":"Reference Ranges | ACP Internal Medicine Meeting. Published 2022. Accessed July 18 2022.Annualmeeting.acponline.org;https:\/\/annualmeeting.acponline.org\/educational\u2010program\/handouts\/reference\u2010ranges\u2010table"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/TME.0000000000000141"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2016.02.041"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-2-274"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.4110"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.18.2263"},{"issue":"2","key":"e_1_2_14_18_1","first-page":"138","article-title":"Anaphylactic and anaphylactoid reactions during the perioperative period","volume":"15","author":"Lagopoulos V","year":"2011","journal-title":"Hippokratia"},{"key":"e_1_2_14_19_1","first-page":"155","article-title":"Drug allergy","volume":"2","author":"Adkinson F","year":"2006","journal-title":"Allergy"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1159\/000479878"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199706000-00038"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2013.02.022"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/22201181.2016.1154309"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2019.11.051"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.05.093"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2015.09.038"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6317956"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6781","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.6781","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:01:34Z","timestamp":1764306094000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.6781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ccr3.6781"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.6781","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"2022-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e6781"}}