{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:06:19Z","timestamp":1764306379061,"version":"3.46.0"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007833","name":"Hamad Medical Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007833","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Chronic myelogenous leukemia is a myeloproliferative neoplasm characterized by the BCR\u2010ABL1 fusion gene and the development of the Philadelphia chromosome, which leads to an increase in granulocytes and bone marrow myeloid precursors in the blood, it can lead to many possible complications depending on the disease stage at the time of diagnosis. The Morel\u2010Lavall\u00e9e lesion (MLL) is a closed traumatic soft\u2010tissue degloving injury, that results from the separation of the hypodermis from the underlying fascia, with resultant hemo\u2010lymphatic fluid collection between the tissue layers. We report a case of a 48\u2010year\u2010old male patient, with no chronic illnesses, who presented with 2\u2009weeks history of posterior chest wall pain and swelling. Initial investigation showed a white blood cell count of 364.4\u00a0\u00d7\u200910\n                    <jats:sup>3<\/jats:sup>\n                    \/\u03bcl. Bone marrow pathology report findings were consistent with chronic myeloid leukemia (CML), and the BCR\u2010ABL test came positive. CT chest with contrast showed a large chest wall lesion, suggestive of a Morel\u2010Lavallee lesion. Ultrasound\u2010guided aspiration of the lesion yielded 20\u2009mm of fluid from the thick hematoma. Histopathology of the fluid showed Necrotic debris with mixed inflammation. Patient's condition improved, and he was discharged on Dasatinib with follow\u2010up in hematology and surgery clinics.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.6807","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:46:54Z","timestamp":1672188414000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chronic myelogenous leukemia presenting with Morel Lavall\u00e9e lesion: A case report of a rare presentation"],"prefix":"10.1002","volume":"10","author":[{"given":"Sara S. I.","family":"Mohamed","sequence":"first","affiliation":[{"name":"Internal Medicine Department Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9354-6314","authenticated-orcid":false,"given":"Hana Mahmoud","family":"Qasim","sequence":"additional","affiliation":[{"name":"Division of Hematology, Oncology Department, National Center for Cancer and Research Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Mahfouz","sequence":"additional","affiliation":[{"name":"Radiology Department Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maab A.","family":"Osman","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraf O. E.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safa H.","family":"Al\u2010Azewi","sequence":"additional","affiliation":[{"name":"Division of Hematology, Oncology Department, National Center for Cancer and Research Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1144-8076","authenticated-orcid":false,"given":"Mohamad A.","family":"Yassin","sequence":"additional","affiliation":[{"name":"Division of Hematology, Oncology Department, National Center for Cancer and Research Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shehab","family":"Fareed","sequence":"additional","affiliation":[{"name":"Division of Hematology, Oncology Department, National Center for Cancer and Research Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.2015.36.5.197"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.d01-1982.x"},{"issue":"7","key":"e_1_2_11_4_1","article-title":"Spontaneous soft tissue haematomas\u2010a rare presentation of chronic myeloid leukemic (CML)","volume":"9","author":"Lakhotia M","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-15-00181"},{"issue":"1","key":"e_1_2_11_6_1","first-page":"42","article-title":"WHO 2016 definition of chronic myeloid leukemia and tyrosine kinase inhibitors","volume":"37","author":"Haznedaro\u011flu \u0130C","year":"2020","journal-title":"Turk J Haematol"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5674193"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/JBM.S71319"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"123","article-title":"Acquired type 2A von Willebrand disease in chronic myelocytic leukemia","volume":"10","author":"Mohri H","year":"1996","journal-title":"Hematopathol Mol Hematol"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.CC.16.00112"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/ejim.ejim_59_18"},{"issue":"2","key":"e_1_2_11_12_1","first-page":"170","article-title":"Chronic myeloid leukemia initially presenting with spontaneous mediastinal hematoma and hemothorax","volume":"63","author":"Kuo YC","year":"2000","journal-title":"Zhonghua Yi Xue Za Zhi"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6807","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.6807","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.6807","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:01:52Z","timestamp":1764306112000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.6807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ccr3.6807"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.6807","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"2022-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e6807"}}