{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T02:13:18Z","timestamp":1778897598090,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T00:00:00Z","timestamp":1498608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Key Clinical Message<\/jats:title>\n                  <jats:p>\n                    Patients with common variable immunodeficiency are prone to infections, and this poses a particular challenge during pregnancy, when the requirement for immunoglobulin (Ig) replacement therapy is even more demanding so as to achieve an effective protection also of the fetus. This case report highlights the benefits observed with subcutaneous IgG self\u2010administration in the management of common variable immunodeficiency (\n                    <jats:styled-content style=\"fixed-case\">CVID<\/jats:styled-content>\n                    ) during pregnancy, in terms of efficacy and safety.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.692","type":"journal-article","created":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T05:06:48Z","timestamp":1498626408000},"page":"1309-1311","source":"Crossref","is-referenced-by-count":7,"title":["Management of common variable immunodeficiency by subcutaneous IgG self\u2010administration during pregnancy \u2013 a case report"],"prefix":"10.1002","volume":"5","author":[{"given":"Carolina","family":"Marasco","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine \u201cG. Baccelli\u201d \u201cAldo Moro\u201d University of Bari Medical School Policlinico Piazza Giulio Cesare 11 I\u201070124 Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberta","family":"Venturelli","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine \u201cG. Baccelli\u201d \u201cAldo Moro\u201d University of Bari Medical School Policlinico Piazza Giulio Cesare 11 I\u201070124 Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigia","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine \u201cG. Baccelli\u201d \u201cAldo Moro\u201d University of Bari Medical School Policlinico Piazza Giulio Cesare 11 I\u201070124 Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Vacca","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine \u201cG. Baccelli\u201d \u201cAldo Moro\u201d University of Bari Medical School Policlinico Piazza Giulio Cesare 11 I\u201070124 Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rosaria","family":"Carrat\u00f9","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Human Oncology Unit of Internal Medicine \u201cG. Baccelli\u201d \u201cAldo Moro\u201d University of Bari Medical School Policlinico Piazza Giulio Cesare 11 I\u201070124 Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07669.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4032"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12178"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.13.30"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2075"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1001\/jama.1982.03320450058038","article-title":"High\u2010dose immunoglobulin replacement therapy by slow subcutaneous infusion during pregnancy","volume":"247","author":"Berger M.","year":"1982","journal-title":"JAMA"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011051704960"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884217504269010"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-010-9423-4"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-011-0036-y"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-013-9876-3"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2165\/00063030-200721020-00005"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccr3.692","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T06:30:33Z","timestamp":1764484233000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,28]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1002\/ccr3.692"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.692","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,28]]}}}