{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T12:26:35Z","timestamp":1759667195249,"version":"3.41.2"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["OAF\u20107369"],"award-info":[{"award-number":["OAF\u20107369"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Endogenous bacterial endophthalmitis results from bacterial seeding of the eye during bacteremia. A diagnosis of endogenous bacterial endophthalmitis requires clinical findings such as vitritis or hypopyon along with positive blood cultures. <jats:italic>Serratia marcescens<\/jats:italic> is the second most common pathogen causing hospital\u2010acquired ocular infections. This report describes a case of endogenous bacterial endophthalmitis caused <jats:italic>by S.\u00a0marcescens<\/jats:italic> in an older adult with end\u2010stage renal disease (ESRD) on peritoneal dialysis, who had late\u2010onset pleural empyema secondary to coronary artery bypass grafting (CABG). A 61\u2010year\u2010old gentleman presented with a two\u2010day history of cloudy vision, black floaters, pain, swelling, and gradual vision loss in his right eye. There was no history of trauma, ocular surgeries, or previous similar episodes. He had myocardial infarction treated with CABG 3 months back. Examination showed a 3\u2009mm hypopyon in the anterior chamber. He had classic signs of endophthalmitis with positive blood cultures for <jats:italic>S.\u00a0marcescens.<\/jats:italic> He was treated with high\u2010dose intravenous meropenem and intravitreal ceftazidime without vitrectomy. Endophthalmitis progressed to complete vision loss in his right eye, requiring evisceration. Endophthalmitis caused by <jats:italic>S.\u00a0marcescens<\/jats:italic> is rare, but long\u2010term outcomes can be severe, causing complete vision loss in about 60% of the patients. It is usually hospital\u2010acquired, and the source can be late\u2010onset empyema several months after cardiac surgery, in an immunocompromised patient. Systemic antibiotics should be supplemented with intravitreal agents with or without pars plana vitrectomy.<\/jats:p>","DOI":"10.1002\/ccr3.6997","type":"journal-article","created":{"date-parts":[[2023,2,25]],"date-time":"2023-02-25T03:33:55Z","timestamp":1677296035000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Endogenous endophthalmitis due to <i>Serratia marcescens<\/i> secondary to late\u2010onset empyema <scp>Post\u2010Cardiac<\/scp> surgery in an <scp>End\u2010Stage<\/scp> renal disease patient on peritoneal dialysis"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4098-0459","authenticated-orcid":false,"given":"Sreethish","family":"Sasi","sequence":"first","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem","family":"Faraj","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja","family":"Barazi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jouhar","family":"Kolleri","sequence":"additional","affiliation":[{"name":"Department of Clinical Imaging Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Chitrambika","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muna A.","family":"Rahman\u00a0Al\u00a0Maslamani","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maisa","family":"Ali","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Department of Internal Medicine Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00017-11"},{"volume-title":"ECDC. 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