{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T07:13:39Z","timestamp":1774595619826,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T00:00:00Z","timestamp":1678147200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a 48\u2010year\u2010old female patient with various stress fractures of extremities, musculoskeletal pain, and tooth loss. Hypophosphatasia was diagnosed based on clinical and laboratory findings and ALPL genetic results. This case highlights the importance of early diagnosis of hypophosphatasia in adults and appropriate treatment to prevent further complications.<\/jats:p>","DOI":"10.1002\/ccr3.7002","type":"journal-article","created":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T04:34:32Z","timestamp":1678250072000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dental loss, stress fractures, and musculoskeletal pain in a 48\u2010year\u2010old woman"],"prefix":"10.1002","volume":"11","author":[{"given":"Lindsay T.","family":"Hoang","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Medicine Walter Reed National Military Medical Center  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Hatfield","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine Walter Reed National Military Medical Center  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Medicine Memorial Hospital West  Pembroke Pines Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5614-6402","authenticated-orcid":false,"given":"Mohamed K. 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