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Optic Neuritis (ON) is not typically seen as a complication of ICHT, and patients diagnosed with concurrent manifestation of both these disorders usually have some identifiable underlying cause. In this report, we highlight the clinical and para\u2010clinical findings in two unrelated children presenting with high CSF opening pressures and Optic neuritis in the absence of any identifiable neurological or immunological cause.<\/jats:p>","DOI":"10.1002\/ccr3.70041","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T08:59:06Z","timestamp":1735635546000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intracranial Hypertension and Optic Neuritis in Two Unrelated Seronegative Cases"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1283-1066","authenticated-orcid":false,"given":"Reza","family":"Nejad Shahrokh Abadi","sequence":"first","affiliation":[{"name":"Clinical Research Development Unit, Ghaem Hospital, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad 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