{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:18:59Z","timestamp":1778753939412,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019779","name":"Qatar National Library","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a case report of a 45\u2010year\u2010old female with acute onset right\u2010sided facial weakness, worsening vision, and diplopia. Upon evaluation, the patient exhibited total right\u2010side facial palsy (House\u2010Brackmann grade IV) with III, IV, and VI Cranial Nerve Ophthalmoplegia. There was no perception of light associated with optic atrophy on ocular examination. Computed tomography and magnetic resonance imaging showed a sizeable sphenoid sinus mass compressing the right optic nerve, consistent with neoplasia or invasive fungal infection. Eventually, we removed the mass endoscopically through a transnasal approach and diagnosed it as invasive Aspergillosis on histopathological examination, even though no previous record of immunodeficiency existed. The patient received intravenous followed by oral voriconazole. Postoperatively, there was partial recovery of her facial nerve function. This case highlights the importance of considering invasive fungal infections, even in immunocompetent patients, when managing space\u2010occupying lesions with neuro\u2010ophthalmic involvement.<\/jats:p>","DOI":"10.1002\/ccr3.70152","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:21:44Z","timestamp":1738826504000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Unmasking Aspergillosis: A Rare Cause of Facial Palsy and Vision Loss in an Immunocompetent Patient\u2014A Case Report and Literature Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6118-717X","authenticated-orcid":false,"given":"Abdur","family":"Rehman","sequence":"first","affiliation":[{"name":"Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafiz Anzal","family":"Farooqi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imran","family":"Khan","sequence":"additional","affiliation":[{"name":"PGY 2 NYH+Hospitals\/Woodlhul  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Akram","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basit Ali","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arham","family":"Ihtesham","sequence":"additional","affiliation":[{"name":"Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahzaib","family":"Maqbool","sequence":"additional","affiliation":[{"name":"Rawalpindi Medical University  Rawalpindi Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2627-685X","authenticated-orcid":false,"given":"Javed","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Nursing Department, Communicable Diseases Center Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmccrj.cr.2020\u20100189"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.55729\/2000\u20109666.1221"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433\u2010019\u20100358\u20106"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof8010033"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2014.7.3.181"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2016.01.007"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.17712\/nsj.2021.4.20210081"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2020.101002"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000001288"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10140\u2010023\u201002117\u2010w"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51571"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2022.08.002"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof6030139"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T08:26:44Z","timestamp":1741768004000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/ccr3.70152"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70152","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70152"}}