{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:26:39Z","timestamp":1780363599055,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This case report presents positive outcomes from deep brain stimulation (DBS) targeting the bed nucleus of the stria terminalis (BNST) in two patients with treatment\u2010resistant depression and generalized anxiety disorder. DBS effects in the medial forebrain bundle (MFB) area were unclear. Further research into DBS's efficacy when comorbid anxiety is present is required.<\/jats:p>","DOI":"10.1002\/ccr3.70179","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T04:59:56Z","timestamp":1738817996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Deep Brain Stimulation in the Bed Nucleus of Stria Terminalis and Medial Forebrain Bundle in Two Patients With Treatment\u2010Resistant Depression and Generalized Anxiety Disorder\u2014A Long\u2010Term Follow\u2010Up"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9679-1609","authenticated-orcid":false,"given":"Matilda","family":"Naesstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Psychiatry Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patric","family":"Blomstedt","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Neurosciences Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3775-7245","authenticated-orcid":false,"given":"Viktoria","family":"Johansson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Psychiatry Ume\u00e5 University  Ume\u00e5 Sweden"},{"name":"Centre for Pharmacoepidemiology, Department of Medicine Solna Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.22746"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/08039488.2016.1162846"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.13649"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-022-01270-3"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.23113"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-021-01861-0"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.856"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.09.015"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.19060656"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2021.01.097"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.124"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301165"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2009.09.013"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/2023.10.JNS231855"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2017.01.581"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-018-0160-4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-022-01504-y"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.19090915"},{"key":"e_1_2_10_20_1","doi-asserted-by":"crossref","unstructured":"S.Siddiqi J.Klingbeil R.Webler et\u00a0al. \u201cCausal Network Localization of Brain Stimulation Targets for Trait Anxiety \u201d2024 https:\/\/www.researchsquare.com\/article\/rs\u20104221074\/v1.","DOI":"10.21203\/rs.3.rs-4221074\/v1"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820080032005"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1985.tb08073.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1959.tb00467.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2011.04.007"},{"key":"e_1_2_10_25_1","unstructured":"Stereotactic Academy \u201cImplanting a DBS System \u201d2020 https:\/\/youtu.be\/89GYugaCt_I."},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2011.07.005"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.323"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-021-04991-0"},{"key":"e_1_2_10_29_1","article-title":"Deep Brain Stimulation for Obsessive\u2010Compulsive Disorder: Optimal Stimulation Sites","volume":"96","author":"Meyer G. M.","year":"2023","journal-title":"Biological Psychiatry"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci14050499"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab170"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.069906"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30371-1"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2013.01.034"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2017.59"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2017.01.006"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2022.03.002"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T02:43:40Z","timestamp":1741747420000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/ccr3.70179"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70179","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70179"}}