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There is a need for practitioners to be aware of the diverse presentation of this disease and the need for further workup. We present two cases of localised oral amyloidosis, outline their investigation and management and review the related literature.<\/jats:p>","DOI":"10.1002\/ccr3.70413","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T06:28:49Z","timestamp":1747290529000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Localized Amyloidosis of the Oral Cavity: A Rare Clinical Entity"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2735-9277","authenticated-orcid":false,"given":"Brian","family":"Maloney","sequence":"first","affiliation":[{"name":"National Maxillofacial Unit St. James's Hospital  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-4059","authenticated-orcid":false,"given":"Veronica","family":"Fisher","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Medicine, Pathology and Radiology Dublin Dental University Hospital, Trinity College  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6903-2455","authenticated-orcid":false,"given":"Claire M.","family":"Healy","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Surgery, Medicine, Pathology and Radiology Dublin Dental University Hospital, Trinity College  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2005.10.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.77.913.686"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0034-3"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2016.1257986"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2003.136"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2022.2147636"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.25761"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2017.1.1"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2018.1549825"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12286"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-1-117"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(03)00026-4"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.12288"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-021-00483-7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13504"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2003.03940.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12870"},{"issue":"4","key":"e_1_2_9_19_1","first-page":"553","article-title":"Head and Neck Manifestations of Amyloidosis","volume":"120","author":"Zundel R. 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